Related Experiment Video
Updated: Jul 4, 2025

A Preclinical Model of Exertional Heat Stroke in Mice
Published on: July 1, 2021
A Novel Conceptual Model for Human Heat Tolerance
Thomas E Bernard1, S Tony Wolf2, W Larry Kenney3
1College of Public Health, University of South Florida, Tampa, FL.
Abstract:
Human "heat tolerance" has no accepted definition or physiological underpinnings; rather, it is almost always discussed in relative or comparative terms. We propose to use environmental limits to heat balance accounting for metabolic rate and clothing, that is, the environments for which heat stress becomes uncompensable for a specified metabolic rate and clothing, as a novel metric for quantifying heat tolerance.
Related Concept Videos
Body Temperature
Requirements for Human Life
Oxygen
Atmospheric air is only about 20 percent oxygen, but that oxygen is a key component of the chemical reactions that keep the body alive, including the reactions that produce ATP. Brain cells are susceptible to a lack of oxygen because they require a...
Mechanism of heat transfer
Mechanisms of Heat Transfer
Conduction, accounting for approximately 3% of body heat loss at rest, is the process of exchanging heat between molecules of two materials in direct contact. This can result in both heat loss and gain. For instance, when the body is submerged in water, which conducts heat 20 times more effectively than air, it can either lose or gain significant...
Thermoregulation
Homeostatic Imbalances in Body Temperature

