Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Urinary Tract Infection II: Pathophysiology

Urinary Tract Infection II: Pathophysiology

The pathophysiology of urinary tract infections (UTIs) encompasses several progressive stages, beginning with bacterial colonization and culminating in potential systemic complications if untreated. UTIs are primarily initiated by bacteria, such as Escherichia coli, which often originate from the gastrointestinal tract and migrate to the urinary system through the periurethral area. This migration can occur via several routes, including improper hygiene practices, sexual activity, or...

Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care

Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care

A healthcare provider can diagnose a urinary tract infection (UTI) through several methods:Medical History and Symptoms: The provider will take a detailed medical history and ask about symptoms such as frequent urination, burning sensation during urination, and lower abdominal pain.Urinalysis: A clean-catch urine sample is collected in a sterile container and tested for the presence of bacteria, white blood cells (leukocytes), nitrites, blood, and protein. The presence of leukocytes and...

Acute Pyelonephritis I: Introduction

Acute Pyelonephritis I: Introduction

Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such as Proteus,...

Acute Pyelonephritis II: Diagnostic Studies and Management

Acute Pyelonephritis II: Diagnostic Studies and Management

Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...

Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations

Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations

Renal calculi, commonly termed kidney stones, are crystalline solid masses that form in the kidneys but can occur at any point within the urinary system, encompassing the kidneys, ureters, bladder, and urethra.The pathophysiology of renal stones involves several key factors: supersaturation of the urine with stone-forming constituents, changes in urine pH, a decrease in urine volume, and the presence of substances that promote or inhibit stone formation.Supersaturation of Urine: This is the...

Urine Studies II: Urine Culture and Sensitivity Test

Urine Studies II: Urine Culture and Sensitivity Test

A urine culture and sensitivity test is a diagnostic procedure used to identify urinary tract bacterial infections and determine the most effective antibiotics for treatment. This test is generally preferred when a patient shows manifestations of a urinary tract infection, such as frequent or painful urination, cloudy or foul-smelling urine, or lower abdominal pain.Purpose of the TestThe primary goals of a urine culture and sensitivity test are to:Determine the specific bacteria causing the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Prevalence and Correlates of Depression among Non-Parturient, Pregnant, and Postpartum Women in Ibadan, Nigeria.

West African journal of medicine·2026

Same author

Knowledge, Attitude and Perception of Medical Students at the University College Hospital, Ibadan towards Female Genital Mutilation.

West African journal of medicine·2025

Same author

A SCOPING REVIEW PROTOCOL ON THE EFFECT OF GYNAECOLOGICAL CANCERS: THEIR DIAGNOSES AND MANAGEMENT ON THE MENTAL HEALTH OF AFFECTED WOMEN IN SUB-SAHARAN AFRICA.

Annals of Ibadan postgraduate medicine·2025

Same author

Prenatal Screening for Down Syndrome: How Acceptable is it among Pregnant Nigerian Women?

West African journal of medicine·2023

Same author

PUERPERAL SEPSIS AT UNIVERSITY COLLEGE HOSPITAL, IBADAN: A 10-YEAR REVIEW.

Annals of Ibadan postgraduate medicine·2023

Same author

Paediatric paranasal sinus fibrous dysplasia.

Tropical doctor·2022

Search research articles

Related Experiment Video

Updated: Jul 14, 2026

A Murine Model of Group B Streptococcus Vaginal Colonization

A Murine Model of Group B Streptococcus Vaginal Colonization

Published on: November 16, 2016

ASYMPTOMATIC BACTERIURIA AS A PREDICTOR OF PRE-ECLAMPSIA: A CASECONTROLLED STUDY.

A A Adeyemo¹, O O Bello^1,2, O C Idowu¹

¹Department of Obstetrics and Gynaecology, University College Hospital, Ibadan, Nigeria.

Annals of Ibadan Postgraduate Medicine

|February 1, 2024

Summary

Asymptomatic bacteriuria in pregnancy is linked to a higher risk of pre-eclampsia. This study found a significant association, suggesting it may be a contributing factor to this serious condition.

More Related Videos

Recurrent Escherichia coli Urinary Tract Infection Triggered by Gardnerella vaginalis Bladder Exposure in Mice

Recurrent Escherichia coli Urinary Tract Infection Triggered by Gardnerella vaginalis Bladder Exposure in Mice

Published on: December 4, 2020

Author Spotlight: Modeling an Aspect of Preeclampsia in Female Mice Using Hypoxic Human Placenta-Derived Small Extracellular Vesicles

Author Spotlight: Modeling an Aspect of Preeclampsia in Female Mice Using Hypoxic Human Placenta-Derived Small Extracellular Vesicles

Published on: January 26, 2024

Related Experiment Videos

Last Updated: Jul 14, 2026

A Murine Model of Group B Streptococcus Vaginal Colonization

A Murine Model of Group B Streptococcus Vaginal Colonization

Published on: November 16, 2016

Recurrent Escherichia coli Urinary Tract Infection Triggered by Gardnerella vaginalis Bladder Exposure in Mice

Recurrent Escherichia coli Urinary Tract Infection Triggered by Gardnerella vaginalis Bladder Exposure in Mice

Published on: December 4, 2020

Author Spotlight: Modeling an Aspect of Preeclampsia in Female Mice Using Hypoxic Human Placenta-Derived Small Extracellular Vesicles

Author Spotlight: Modeling an Aspect of Preeclampsia in Female Mice Using Hypoxic Human Placenta-Derived Small Extracellular Vesicles

Published on: January 26, 2024

Area of Science:

Obstetrics and Gynecology
Infectious Diseases
Maternal Health

Background:

Pre-eclampsia is a major global cause of maternal and perinatal mortality.
Subclinical infections, including asymptomatic bacteriuria, are implicated in pre-eclampsia's development.
Asymptomatic bacteriuria is a common finding during pregnancy.

Purpose of the Study:

To investigate the relationship between asymptomatic bacteriuria and pre-eclampsia.
To determine if asymptomatic bacteriuria acts as a risk factor for developing pre-eclampsia.

Main Methods:

A hospital-based case-control study involving 28 pre-eclamptic women and 56 healthy pregnant women (controls).
Participants were at least 28 weeks of gestation.
Asymptomatic bacteriuria was diagnosed via mid-stream urine microscopy and culture; data collected through questionnaires and medical records.

Main Results:

A significant association was found between asymptomatic bacteriuria and pre-eclampsia.
Women with pre-eclampsia had approximately three times the rate of asymptomatic bacteriuria compared to controls (OR: 2.9).
After adjusting for confounders, the adjusted odds ratio remained significant (AOR: 1.23).

Conclusions:

The study supports asymptomatic bacteriuria as a risk factor for pre-eclampsia.
The causal nature of this association requires further investigation.
Additional research is needed to elucidate the relationship between asymptomatic bacteriuria and pre-eclampsia.