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Updated: Jul 4, 2025

Murine Hind Limb Long Bone Dissection and Bone Marrow Isolation
Published on: April 14, 2016
[Metabolic bone diseases : what's new in 2023]
Serge Ferrari1, Andrea Trombetti1, Anne-Cecile Debrach1
1Service des maladies osseuses, Département de médecine, Hôpitaux universitaires de Genève, 1211 Genève 14.
None:
The sequential effects of romosozumab and denosumab in osteoporosis are shown in real-life, while the mechanisms of post-denosumab rebound are reviewed extensively. A network meta-analysis confirms the superiority of anabolics vs anti-resorptives on fracture reduction, while the latter shown a reduction of mortality in a large population-based study. Fracture risk prediction by FRAXPlus is improved. New meta-analyses confirm the benefits of Vitamin D on fractures and falls. Finally, multiples trials with new molecules for the treatment of rare bone diseases, including osteogenesis imperfecta, fibrous dysplasia and hypoparathyroidism, shown promising results.
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