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Related Experiment Video

Updated: Jul 4, 2025

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PERSIAN Eye Cohort Study (PECS): Design, Methodology.

Fateme Alipour1, Hassan Hashemi2, Alireza Lashay1

  • 1Translational Ophthalmology Research Center, Farabi Eye Hospital, Department of Ophthalmology, Tehran University of Medical Sciences, Tehran, Iran.

Archives of Iranian Medicine
|February 1, 2024
PubMed
Summary

The PERSIAN Eye Cohort Study (PECS) is a large, multi-center epidemiological study investigating eye conditions in Iran. It aims to understand the prevalence and risk factors of ophthalmic disorders across diverse regions and ethnicities.

Keywords:
Cohort studyEpidemiologyIranOphthalmology

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Area of Science:

  • Ophthalmology
  • Epidemiology
  • Public Health

Background:

  • The PERSIAN Eye Cohort Study (PECS) is an extension of the PERSIAN Cohort Study.
  • It aims to investigate the distribution and determinants of ophthalmic disorders in Iran.

Purpose of the Study:

  • To report the protocol, methodology, and enrollment data of PECS.
  • To explore the associations between ophthalmic conditions and various exposures.
  • To inform future nationwide and global eye health interventions.

Main Methods:

  • A multi-center design involving six selected sites across Iran.
  • Standardized study protocols and central committee oversight.
  • Data collection including slit lamp and fundus photography.

Main Results:

  • Launched in 2014, PECS enrolled 48,618 participants aged 35-70 by June 2021 (74.13% response rate).
  • Ophthalmic examinations were conducted on a significant portion of the enrolled cohort.

Conclusions:

  • PECS provides valuable epidemiological data on prevalent eye disorders in Iran.
  • Findings will enhance understanding of regional and ethnic variations in eye health.
  • The study will support evidence-based public health strategies for eye care.