Related Experiment Video
Updated: Jul 4, 2025

Teasing Out the Interplay Between Natural Killer Cells and Nociceptor Neurons
Published on: June 30, 2022
Evolutionary edge: NOD-like receptors in immunity
1Freelance Journalist, Berlin, Germany.
Abstract:
This issue of the Biomedical Journal delves into the multifaceted roles of NOD-like receptors (NLRs) in immunity, examining their subfamilies and functions within innate and adaptive immunity, autoimmune and inflammatory conditions, and mitophagy regulation. In this issue the dynamics of mRNA vaccines are explored, as well as the synergistic effects of a ketogenic diet with anti-tumor therapies, the roles of curcumin and RANKL in osteoclastogenesis, and the validation of a rapid diagnostic test for an oral cancer biomarker. Additionally, advancements in ocular care are highlighted, featuring a novel prodrug targeting corneal neovascularization, and discussing the efficacy of dexamethasone implants against macular edema. Concluding, further insights into the impact of sweetened foods on child development are given.
Related Concept Videos
Diversity of Antigen Receptors
Before encountering any antigen, lymphocytes express these receptors. On B cells, the antigen receptor is a membrane-bound antibody molecule called BCR; on T cells, it is a T cell receptor or TCR. B and T cell receptors are composed of two...
NF-κB-dependent Signaling Pathway
NF-κB-dependent Signaling Mechanism
The...
Notch Signaling Pathway
The Notch gene came into the limelight in 1914 after the discovery that its mutation in Drosophila melanogaster leads to a serrated (or "notched") wing margin phenotype. It was not...
Cells of the Innate Immune Response
Phagocytes
Phagocytes police the peripheral tissues by removing cellular debris and responding to the invasion of foreign substances or pathogens. Many phagocytes attack and remove microorganisms even before lymphocytes detect them. The human body has two general...
Role Of Notch Signalling In Intestinal Stem Cell Renewal
Direct cell-to-cell contact is needed for the activation of Notch signaling. The signal is initiated when a notch ligand binds to a receptor on an adjacent cell, also...
Cytotoxic T Cells-mediated Immune Response
Immunological surveillance is the ability of immune cells to monitor and eliminate infected cells with intracellular pathogens, neoplastically transformed cells, and cells with non-self antigens. Cytotoxic T cells and NK...

