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Updated: Jul 4, 2025

Bovine Mammary Gland Biopsy Techniques
Published on: December 23, 2018
IgG4-related mastitis managed without excision or steroid therapy
Hirokazu Matsushima1, Masayuki Kikuchi2, Rika Miyabe3
1Department of Surgery, Japanese Red Cross Shizuoka Hospital, 8-2, Ottemachi, Aoi-Ku, Shizuoka, Shizuoka, 420-0853, Japan.
Abstract:
IgG4-related mastitis is an extremely rare IgG4-related sclerosing disease involving the breast that must be differentiated from breast cancer. There is currently no consensus regarding the optimal treatment strategies. Here, we report a case of IgG4-related mastitis followed up without excision or steroid therapy. Although the association between IgG4-related mastitis and breast cancer remains unclear, regular follow-up imaging and measurement of serum concentrations of disease activity markers may allow for follow-up without excision or steroid therapy.
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