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Updated: May 8, 2026

Murine Model of Hindlimb Ischemia
Published on: January 21, 2009
Unilateral upper and lower limb ischemia mimics stroke: a case report
Monika Péčová1,2, Jakub Benko3,4, Martin Jozef Péč5
1Oncology Centre, Teaching Hospital Martin, Kollárova 2, 036 01, Martin, Slovakia.
Acute limb ischemia can mimic stroke, presenting with similar unilateral symptoms. This case highlights the importance of thorough evaluation to differentiate these conditions and ensure timely surgical revascularization for successful outcomes.
Area of Science:
- Vascular Surgery
- Neurology
- Emergency Medicine
Background:
- Stroke and acute limb ischemia (ALI) can present with overlapping unilateral symptoms, challenging initial diagnosis.
- Prompt differentiation is critical as both conditions require distinct and timely therapeutic interventions to prevent irreversible damage.
- Awareness of these potential diagnostic mimics is essential for clinicians managing patients with acute neurological or vascular events.
Observation:
- A 69-year-old patient presented with unilateral paresthesia, initially suspected as stroke.
- Despite a negative brain computed tomography (CT) scan, persistent evaluation revealed acute left-sided upper and lower limb ischemia.
- The patient had known atherosclerotic risk factors, a crucial piece of history.
Findings:
- The patient underwent successful surgical revascularization for acute unilateral upper and lower limb ischemia.
- The diagnosis of ALI was confirmed after excluding stroke through comprehensive examination and imaging.
- The patient experienced a satisfactory recovery and was discharged shortly after the procedure.
Implications:
- This case underscores the necessity of considering ALI as a stroke mimic, especially in patients with unilateral limb symptoms.
- Persistent diagnostic efforts and repeated reevaluations are vital for accurate diagnosis in complex presentations.
- Recognizing and managing rare conditions like unilateral ALI that mimic stroke can lead to successful treatment and improved patient outcomes.
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