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Published on: December 11, 2016
Relationship between Earlobe Crease and Anatomical Severity of Coronary Artery Disease in ST-segment Elevation
Ryota Kaichi1, Shoji Kawakami1,2, Yoshio Tahara1
1Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Japan.
Insights
Earlobe crease (ELC) presence indicates more severe coronary artery disease (CAD) in ST-segment elevation myocardial infarction (STEMI) patients. This finding aids in assessing cardiovascular risk and guiding urgent treatment decisions.
Area of Science:
- Cardiology
- Medical Diagnostics
Background:
- Earlobe crease (ELC) is a potential physical marker for cardiovascular disease.
- The association between ELC and coronary artery disease (CAD) severity, particularly in ST-segment elevation myocardial infarction (STEMI) patients, remains unclear.
Purpose of the Study:
- To investigate the relationship between ELC and the anatomical severity of CAD.
- To utilize the residual SYNTAX score to quantify CAD severity in STEMI patients with and without ELC.
Main Methods:
- A study involving 219 consecutive STEMI patients, categorized by the presence or absence of ELC.
- Assessment of CAD severity using the residual SYNTAX score post-percutaneous coronary intervention.
Main Results:
- Patients with ELC exhibited a significantly higher number of diseased coronary vessels compared to those without ELC.
- The ELC group had a higher median residual SYNTAX score, indicating more complex CAD.
- ELC was identified as an independent predictor of the residual SYNTAX score.
Conclusions:
- ELC is significantly associated with greater anatomical severity of coronary artery disease in STEMI patients.
- ELC can serve as a valuable clinical sign for assessing CAD severity in emergency settings.
Abstract:
Objective Earlobe crease (ELC) is an easily detectable physical sign of cardiovascular risk and coronary artery disease (CAD). However, the relationship between ELC and CAD severity in patients with ST-segment elevation myocardial infarction (STEMI) requiring urgent clinical judgment is unknown. Using the residual synergy between percutaneous coronary intervention with taxus and cardiac surgery (SYNTAX) score, we investigated the relationship between ELC and anatomical severity of CAD. Methods We studied 219 consecutive patients with STEMI (median age, 71 years old) and divided them into 2 groups according to the presence of ELC (ELC group, n=161; non-ELC group, n=58). Results The ELC group had a significantly higher number of diseased vessels than the non-ELC group (≥2 diseased vessels, 79% vs. 46%; ≥3 diseased vessels, 35% vs. 12%; p<0.001). In addition, a higher median residual SYNTAX score was observed after primary percutaneous coronary intervention than the non-ELC group [8 (4-12) vs. 3 (0-8), p<0.001]. Furthermore, a multivariable regression analysis showed that ELC was an independent predictor of the residual SYNTAX score (β=3.620, p<0.001). Conclusions The presence of ELC was significantly associated with the anatomical severity of diseased coronary vessels in patients with STEMI who required emergency clinical judgment and treatment.
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