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Published on: July 21, 2013
Use of MLC901 in cerebral venous sinus thrombosis: Three case reports
Anita Ante Arsovska1, Narayanaswamy Venketasubramanian2
1Department of Urgent Neurology, University Clinic of Neurology, University Ss. Cyril and Methodius-Faculty of Medicine, Skopje 1000, North Macedonia. anita70mk@yahoo.com.
Insights
Cerebral venous sinus thrombosis (CVST) patients showed improved outcomes when treated with NeuroAiD II™ (MLC901) alongside standard care. This herbal treatment was well-tolerated and demonstrated potential in aiding recovery from this rare cerebrovascular condition.
Area of Science:
- Neurology
- Pharmacology
- Herbal Medicine
Background:
- Cerebral venous sinus thrombosis (CVST) is a rare cerebrovascular disease affecting young adults, with limited treatment options.
- Early diagnosis and intervention are crucial for favorable outcomes in CVST patients.
- NeuroAiD II™ (MLC901) is a natural herbal formulation investigated for its potential in post-stroke recovery.
Background:
Cerebral venous sinus thrombosis (CVT) is rare cause of cerebrovascular disease. The incidence is 0.5% of all stroke. The majority of affected patients are young adults (mean age: 35-40 years) with mild to moderate disabilities. Poor outcome with severe disability is seen in 13% of cases. Early diagnosis and treatment are important for good outcomes and preventing complications. Treatment options are limited and mostly based on consensus. NeuroAiD II™ (MLC901; Moleac Pte, Ltd, Singapore) has a potential beneficial role in post-stroke recovery, by aiding the natural brain recovery process.
Case Summary:
MLC901 consists of nine natural herbal ingredients. Studies have shown its safety profile and aid in post stroke recovery. The aim of this case series was to demonstrate the potential role of MLC901 in stroke recovery of patients with cerebral venous sinus thrombosis (CVST) who received MLC901 in addition to standard of care. The prescribed dose of MLC901 is 400 mg/cap two capsules, three times a day. Data from these patients were prospectively collected at baseline and at monthly visits, for a duration of 3 mo. Outcome measures included adherence to therapy, side effects, National Institutes of Health Stroke Scale, Glasgow Coma Scale, modified Rankin Scale, and the Short Orientation-Memory-Concentration Test. MLC901 was well tolerated and no side effects were reported. All patients were stable with improved condition.
Conclusion:
This case series highlights the potential therapeutic effects of MLC901 on CVST and provides support for further studies.
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