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Updated: Jul 4, 2025
08:16
Intra-Operative Neural Monitoring of Thyroid Surgery in a Porcine Model
Published on: February 11, 2019
21.3K
Ketamine infiltration improves analgesia after thyroid surgery.
Moncef Sellami1,2,3, Imen Zouche1,2,4, Mariam Ben Ayed1,2,3
1Faculty of Medicine of Sfax, Sfax, Tunisia.
F1000Research
|February 5, 2024
Summary
Ketamine wound infiltration effectively reduced postoperative pain and opioid requirements in thyroid surgery patients compared to a saline placebo. This method offers a safe and efficient approach to managing post-thyroidectomy pain.
Area of Science:
- Anesthesiology
- Surgical Pain Management
Background:
- Postoperative pain following thyroid surgery can lead to complications and chronic pain.
- Effective pain management is crucial for patient recovery and preventing adverse outcomes.
Purpose of the Study:
- To assess the efficacy of ketamine wound infiltration versus placebo in mitigating postoperative pain.
- To evaluate the impact on analgesic requirements after thyroidectomy.
Main Methods:
- A randomized controlled trial involving patients undergoing thyroid surgery.
- Patients received either ketamine (2 mg/kg) or saline wound infiltration.
- Pain was measured using Visual Analog Scale (VAS) and opioid consumption was recorded.
Main Results:
- Ketamine group showed significantly lower VAS scores postoperatively compared to the placebo group.
- Opioid consumption in the post-anesthetic care unit (PACU) was significantly reduced in the ketamine group (0 mg vs. 0.71 mg).
- Nausea and vomiting incidence was comparable between groups.
Conclusions:
- Ketamine wound infiltration is an effective strategy for reducing postoperative pain and opioid use after thyroid surgery.
- This technique presents a valuable option for enhancing patient comfort and recovery post-thyroidectomy.
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