Related Experiment Video

Updated: May 6, 2026

Minimally Invasive Endoscopic Intracerebral Hemorrhage Evacuation
09:01

Minimally Invasive Endoscopic Intracerebral Hemorrhage Evacuation

Published on: October 15, 2021

7.7K

Persistent convex ST-segment elevation in a patient with a history of prior intracerebral haemorrhage

Jian Jiang1,2, Chengjiang Jin3,4,5, Shuo Yu6

  • 1The Second Affiliated Hospital (Quzhou Campus), School of Medicine, Zhejiang University, Quzhou, China.

ESC Heart Failure
|February 7, 2024
PubMed

Insights

Identifying the cause of ST-segment elevation on electrocardiograms (ECGs) is crucial for chest pain management. This case highlights a rare instance of persistent ST-segment elevation not caused by myocardial infarction, emphasizing the need for comprehensive diagnosis.

Area of Science:

  • Cardiology
  • Medical Diagnostics

Background:

  • Acute chest pain management requires prompt identification of ST-segment elevation myocardial infarction (STEMI) using electrocardiograms (ECGs).
  • ST-segment elevation on ECGs can mimic STEMI but also arise from diverse cardiac and non-cardiac conditions, complicating differential diagnosis.

Observation:

  • A 52-year-old female presented with chest pain and unexplained convex ST-segment elevation on ECG.
  • Diagnostic workup, including emergent coronary angiography and echocardiography, yielded normal results.

Findings:

  • The ST-segment elevation persisted for over a year without evidence of myocardial infarction.
  • The final diagnosis was non-myocardial infarction, potentially linked to a prior cerebral hemorrhage.

Implications:

  • This case underscores the importance of considering non-myocardial infarction causes for ST-segment elevation, even when persistent.
  • Thorough patient history and examination are essential for accurate diagnosis when ECG findings are ambiguous or atypical.

Keywords:
Differential diagnosisECGIntracerebral haemorrhageST‐segment elevationST‐segment elevation myocardial infarction

More Related Videos

Brain Infarct Segmentation and Registration on MRI or CT for Lesion-symptom Mapping10:25

Brain Infarct Segmentation and Registration on MRI or CT for Lesion-symptom Mapping

Published on: September 25, 2019

48.1K
Pre-Chiasmatic, Single Injection of Autologous Blood to Induce Experimental Subarachnoid Hemorrhage in a Rat Model09:14

Pre-Chiasmatic, Single Injection of Autologous Blood to Induce Experimental Subarachnoid Hemorrhage in a Rat Model

Published on: June 18, 2021

2.3K

Related Concept Videos

Ischemic Stroke l: Introduction01:15

Ischemic Stroke l: Introduction

Ischemic stroke is an acute cerebrovascular condition in which blood flow to a brain region is suddenly interrupted, leading to tissue infarction. Neurons depend on continuous oxygen and glucose supply, so even brief reductions in perfusion cause energy failure, ionic imbalance, and irreversible injury. Ischemic strokes are classified into thrombotic and embolic types based on their underlying mechanisms.Thrombotic MechanismsThrombotic stroke develops when a clot forms within a cerebral artery.
53
Ischemic Stroke ll: Pathophysiology01:15

Ischemic Stroke ll: Pathophysiology

An ischemic stroke occurs when a cerebral blood vessel becomes obstructed, most often by a thrombus or embolus, interrupting the delivery of oxygen and glucose to brain tissue. Because neurons rely on continuous aerobic metabolism, energy failure begins within minutes of reduced perfusion. The region receiving the least blood flow becomes the infarct core, an area of irreversible cellular death. Surrounding this core lies the penumbra, a zone of hypoperfused but still viable tissue that is...
68
Hemorrhagic Stroke l: Introduction01:17

Hemorrhagic Stroke l: Introduction

A hemorrhagic stroke is an acute neurological event that occurs when a weakened cerebral blood vessel ruptures, allowing blood to accumulate within or around the brain. The sudden release of blood forms a focal hematoma that increases intracranial pressure, displaces neural tissue, and can obstruct cerebrospinal fluid pathways. These effects may be compounded by intraventricular extension of the hemorrhage, cerebral edema, or compression of adjacent structures, all of which contribute to...
34
Hemorrhagic Stroke ll: Pathophysiology01:29

Hemorrhagic Stroke ll: Pathophysiology

A hemorrhagic stroke develops when a cerebral blood vessel ruptures, allowing blood to escape into the surrounding brain tissue, as in intracerebral hemorrhage (ICH), or into the subarachnoid space, as in subarachnoid hemorrhage (SAH). Because the skull is a rigid compartment, the sudden presence of extravascular blood rapidly increases intracranial pressure and compresses adjacent neural structures, leading to immediate tissue injury and impaired cerebral perfusion.Mass Effect and Primary...
52
Transient Ischemic Attack l: Introduction01:26

Transient Ischemic Attack l: Introduction

A transient ischemic attack (TIA) is a brief episode of neurological dysfunction caused by a temporary, focal reduction in cerebral blood flow. Although symptoms resemble those of an ischemic stroke, the interruption in perfusion is short-lived and does not cause permanent infarction. TIAs are clinically important because they often serve as early warning events for future stroke.Mechanisms of Transient Cerebral IschemiaTransient cerebral ischemia may arise through several mechanisms. One...
34
Cerebral Edema ll: Pathophysiology01:22

Cerebral Edema ll: Pathophysiology

Vasogenic edema is a major form of cerebral edema characterized by abnormal accumulation of fluid in the brain’s extracellular space due to disruption of the blood–brain barrier (BBB). The BBB is a specialized structure composed of endothelial cells connected by tight junctions, supported by astrocytic endfeet and a basement membrane. Under normal conditions, it tightly regulates the movement of ions, proteins, and solutes between the bloodstream and brain parenchyma. When this...
31