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The Barium Swallow Study, or a Barium Esophagogram, is a diagnostic imaging method used to visualize the upper gastrointestinal (GI) tract, including the esophagus, stomach, and small intestine. It employs barium sulfate, a radiopaque contrast material, to provide clear images of the upper digestive system, helping to identify abnormalities, diseases, or structural issues.
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Enteral Nutrition I: Orogastric and Nasogastric Feeding01:26

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Enteral nutrition delivers nutrients directly to the stomach or small intestine through a tube. This method is appropriate for patients who cannot eat but still have a functioning digestive system. It is also beneficial for individuals with swallowing difficulties, anorexia, malabsorption, or those who have undergone gastrointestinal (GI) surgery.
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Related Experiment Video

Updated: Jul 4, 2025

Adapting Human Videofluoroscopic Swallow Study Methods to Detect and Characterize Dysphagia in Murine Disease Models
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Oxaliplatin-related dysphagia: Mixed-methods study.

Ciarán Kenny1, Julie Regan2, Lucy Balding3

  • 1Department of Clinical Speech and Language Studies, University of Dublin Trinity College, Dublin, Ireland ckenny9@tcd.ie.

BMJ Supportive & Palliative Care
|February 7, 2024
PubMed
Summary
This summary is machine-generated.

Oxaliplatin chemotherapy is linked to unusual swallowing problems, including temperature sensitivity and throat sensations. These atypical dysphagia symptoms require further study to aid patient nutrition and enjoyment of meals.

Keywords:
CancerDrug administrationDysphagiaSupportive care

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Area of Science:

  • Oncology
  • Gastroenterology
  • Clinical Pharmacy

Background:

  • Dysphagia is a common concern in cancer patients.
  • Chemotherapy agents can cause various side effects impacting quality of life.
  • Understanding specific drug-related toxicities is crucial for supportive care.

Purpose of the Study:

  • To investigate atypical dysphagia symptoms experienced by patients undergoing oxaliplatin treatment.
  • To determine the association between oxaliplatin therapy and specific swallowing difficulties.

Main Methods:

  • An observational study involving 73 adult cancer patients with dysphagia.
  • Data collected via semistructured interviews and the Oral Health Assessment Tool.
  • Content analysis of interview responses and Fischer's Exact test for statistical association.

Main Results:

  • Oxaliplatin treatment correlated with unusual dysphagia symptoms: issues with hot/cold bolus (p=0.01), paresthesia (p=0.001), and throat spasm (p=0.035).
  • Chemotherapy commencement preceded swallow problem onset in 67% of participants.
  • Dysphagia symptoms were not linked to mucositis (p=0.165).

Conclusions:

  • Atypical dysphagia in oxaliplatin-treated patients is likely attributable to chemotherapy.
  • Beyond cold, hot and carbonated boluses can trigger dysphagia in these patients.
  • Further research into dysphagia symptoms and triggers is needed to prevent malnutrition and improve patient well-being.