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EBV-associated lymphoproliferative disease post-CAR-T cell therapy

Shiyuan Zhang1,2, Xiaoxi Zhou1,2, Shangkun Zhang3

  • 1Department of Hematology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.

Frontiers of Medicine
|February 8, 2024
PubMed
Summary

Epstein-Barr virus (EBV)-associated lymphoproliferative diseases (EBV-LPDs) can occur long after chimeric antigen receptor T-cell (CAR-T) therapy. These EBV-LPDs were successfully treated with immune checkpoint inhibitors or B-cell depleting agents.

Keywords:
EBV-associated lymphoproliferative diseaseautologous stem cell transplantationchimeric antigen receptor T-cellimmune checkpoint inhibitor

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