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SOX on tumors, a comfort or a constraint?

Junqing Jiang1, Yufei Wang1, Mengyu Sun1

  • 1Department of Gastroenterology, Institute of Liver and Gastrointestinal Diseases, Hubei Key Laboratory of Hepato-Pancreato-Biliary Diseases, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, Hubei Province, China.

Cell Death Discovery
|February 8, 2024
PubMed
Summary

The SOX (SRY-related HMG box) family of transcription factors plays a critical role in cell fate and is implicated in various cancers. This review explores their complex roles in tumorigenesis and the tumor immune microenvironment (TIME).

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