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Genetic analysis of cardiac dynamic flow volumes identifies loci mapping aortic root size

Patricia B Munroe1, Nay Aung2,3, Julia Ramírez2,4,5

  • 1William Harvey Research Institute, Barts and the London Faculty of Medicine and Dentistry, Queen Mary University of London, London, UK. p.b.munroe@qmul.ac.uk.

Nature Genetics
|February 9, 2024
PubMed
Abstract

No abstract available in PubMed .

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Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...
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