Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Tumor Progression02:07

Tumor Progression

6.2K
Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
6.2K
Overview of Systemic Arteries01:11

Overview of Systemic Arteries

2.6K
The human body is a complex, well-organized machine, and at the heart of its operations lies the circulatory system. This network of blood vessels, which includes systemic arteries, plays a vital role in maintaining life by transporting nutrients, oxygen, and waste products to and from cells throughout the body.
Systemic circulation is the part of the cardiovascular system that carries oxygenated blood away from the heart to the body's tissues and returns deoxygenated blood back to the...
2.6K
Peripheral Artery Disease I: Introduction01:30

Peripheral Artery Disease I: Introduction

659
Peripheral artery disease (PAD) predominantly results from atherosclerosis, which involves the accumulation of fatty deposits, or plaques, within the walls of arteries. This causes them to narrow and harden, significantly reducing blood flow. PAD predominantly affects the legs, particularly the arteries supplying the thighs and calves. In rare cases, it may involve other arteries, including those in the arms.Etiology of PAD:The principal cause of PAD is atherosclerosis, which results from fatty...
659
Aneurysm II: Clinical Manifestations and Diagnostic Studies01:21

Aneurysm II: Clinical Manifestations and Diagnostic Studies

589
Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
589
Varicose Veins II: Diagnostic Studies and Interprofessional Care01:26

Varicose Veins II: Diagnostic Studies and Interprofessional Care

319
Varicose veins, or varicosities, develop when the valves in the veins, which control blood flow, weaken or damage. It causes blood to pool and the veins to enlarge. Understanding the clinical manifestations, diagnostic approaches, and management options for varicose veins is crucial for effective treatment and relief.Clinical manifestationsClinical manifestations of varicose veins include a heavy, achy feeling or pain after prolonged standing or sitting. This discomfort can often be relieved by...
319
Imaging Studies VII: Vascular Imaging01:19

Imaging Studies VII: Vascular Imaging

558
DefinitionRenal angiography, also known as renal arteriography, is an imaging technique used to obtain a comprehensive view of blood flow and the vascular structure of blood vessels in the kidneys and surrounding areas.PurposeRenal angiography detects blood vessel abnormalities in the kidneys, such as aneurysms, stenosis, thrombosis, vascular tumors, and renal artery stenosis. It evaluates kidney function and guides interventional treatments like angioplasty or stent placement.Pre-Procedure...
558

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Layer-specific facial soft-tissue thickness in 1174 Chinese adults: Implications for finite-element headforms and ergonomic design.

Ergonomics·2026
Same author

An HOCl-Activated Acyl Hydrazide Platform for Fluorescence-Guided Release of Hydroxyl-Containing Drugs.

Analytical chemistry·2026
Same author

Tobacco exposure and peripheral artery disease: A multi-omics investigation integrating epidemiology, genetics, toxicology, and single-cell transcriptomics.

Ecotoxicology and environmental safety·2026
Same author

Microenvironment-Targeted Nanomedicine for Diagnosis and Treatment of Atherosclerosis.

Tissue engineering. Part B, Reviews·2026
Same author

Correction: Mid- and long-term evaluation of an alternative to the Liu' modified Bentall procedure for aortic root aneurysm.

Frontiers in cardiovascular medicine·2026
Same author

Ferroptosis inhibition mitigates glyphosate-induced inflammation and blood-milk barrier disruption in bovine mammary epithelial cells.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association·2025
Same journal

Association of miR-133a With Microalbuminuria in Patients With Resistant Arterial Hypertension and Chronic Kidney Disease.

Medical science monitor : international medical journal of experimental and clinical research·2026
Same journal

Levofloxacin-Induced Cutaneous Adverse Reactions: Characteristics and Rational Use Strategies.

Medical science monitor : international medical journal of experimental and clinical research·2026
Same journal

Presence and Impact of Fatigue in Patients With Multiple Sclerosis.

Medical science monitor : international medical journal of experimental and clinical research·2026
Same journal

Evaluation of Salivary Total Oxidant Status (TOS) and Total Antioxidant Status (TAS) in Orthodontic Patients Treated With Clear Aligners vs Conventional Brackets.

Medical science monitor : international medical journal of experimental and clinical research·2026
Same journal

Combined Fibrinogen and Urinary α1-Microglobulin as Predictors of Respiratory Tract Infection in Children with Nephrotic Syndrome.

Medical science monitor : international medical journal of experimental and clinical research·2026
Same journal

Comparison of Radiographic Cervical Sagittal Alignment Parameters in Patients With Nonspecific Neck Pain, Degenerative Neck Pain, and Healthy Individuals.

Medical science monitor : international medical journal of experimental and clinical research·2026
See all related articles

Related Experiment Video

Updated: May 2, 2026

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
12:17

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots

Published on: May 21, 2017

11.3K

Research Progress on Aortic Root Aneurysms.

Tonghua Du1, Weitie Wang1, Yong Wang1

  • 1Department of Cardiovascular Surgery, Second Hospital of Jilin University, Changchun, Jilin, China (mainland).

Medical Science Monitor : International Medical Journal of Experimental and Clinical Research
|February 9, 2024
PubMed
Summary
This summary is machine-generated.

Aortic root aneurysms are dangerous, often fatal conditions. Advances in surgical and medical treatments offer improved survival rates for patients with aortic root disease.

More Related Videos

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement
14:14

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement

Published on: December 11, 2017

14.1K
Author Spotlight: Development and Characterization of a Mouse Model for Abdominal Aortic Aneurysm
05:07

Author Spotlight: Development and Characterization of a Mouse Model for Abdominal Aortic Aneurysm

Published on: August 2, 2024

854

Related Experiment Videos

Last Updated: May 2, 2026

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
12:17

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots

Published on: May 21, 2017

11.3K
Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement
14:14

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement

Published on: December 11, 2017

14.1K
Author Spotlight: Development and Characterization of a Mouse Model for Abdominal Aortic Aneurysm
05:07

Author Spotlight: Development and Characterization of a Mouse Model for Abdominal Aortic Aneurysm

Published on: August 2, 2024

854

Area of Science:

  • Cardiovascular Medicine
  • Aortic Diseases
  • Surgical Innovation

Background:

  • Aortic root aneurysms are common, life-threatening conditions involving the aortic valve, sinus, coronary arteries, and ascending aorta.
  • High mortality (approx. 90%) is linked to rupture; common complications include aortic valve insufficiency leading to heart failure.
  • Etiology includes genetic factors (Marfan syndrome), atherosclerosis, and secondary causes like aortic valve stenosis.

Approach:

  • Review of current research on aortic root aneurysm etiology, complications, and treatment modalities.
  • Analysis of traditional and novel therapeutic strategies, including medical management and surgical interventions.
  • Evaluation of advancements in aortic root replacement techniques and personalized treatment approaches.

Key Points:

  • Surgical aortic root replacement is a primary treatment, but carries high perioperative risks, especially in high-risk patients.
  • Evolving treatments include conservative drug therapy (beta-blockers, ACE inhibitors, ARBs), Bentall and modified Bentall surgeries, valve-sparing procedures (David, Yacoub), external aortic root support, and endovascular interventions.
  • These advanced methods have significantly improved patient survival rates.

Conclusions:

  • Individualized treatment strategies based on refined anatomical understanding are crucial for managing aortic root aneurysms.
  • While various treatments offer improved outcomes, each possesses distinct advantages and disadvantages requiring careful consideration.
  • Continued research and refinement of therapeutic approaches are essential for optimizing patient care and long-term survival.