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A five-day-old child with lipid hemihypertrophy: A case report
Kayvan Mirnia1, Maryam Saeedi1, Razieh Sangsari1
1Division of Neonatology, Department of Pediatrics, Children's Medical Center, Pediatric Center of Excellence, Faculty of Medicine Tehran University of Medical Sciences Tehran Iran.
Clinical Case Reports
|February 9, 2024
Summary
Lipid hemihypertrophy, a rare condition causing localized overgrowth, requires early diagnosis in newborns. Prompt evaluation is crucial for managing associated conditions and potential complications in infants.
Area of Science:
- Medical Case Reports
- Pediatric Endocrinology
- Clinical Genetics
Background:
- Neonatal asymmetry presents a diagnostic challenge, necessitating a broad differential diagnosis.
- Lipid hemihypertrophy is a rare congenital condition characterized by localized overgrowth of adipose tissue.
- Timely identification of neonatal asymmetry is critical for appropriate clinical management.
Observation:
- A 5-day-old female neonate presented with unilateral enlargement affecting the right thigh, labia majora, and submandibular region.
- The observed asymmetry was attributed to lipid hemihypertrophy, a condition involving excessive fat tissue growth.
- Clinical examination revealed significant localized adipose tissue proliferation.
Findings:
- Lipid hemihypertrophy was diagnosed based on clinical presentation and characteristic localized overgrowth.
- The case underscores the importance of considering lipid hemihypertrophy in the differential diagnosis of neonatal asymmetry.
- Associated disorders were not explicitly detailed but are a key consideration for management.
Implications:
- Early recognition of lipid hemihypertrophy facilitates prompt evaluation for potential syndromic associations.
- Multidisciplinary management is essential for optimizing long-term outcomes and quality of life in affected neonates.
- Comprehensive assessment and surveillance are vital for managing complications associated with lipid hemihypertrophy.
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