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Published on: January 6, 2023
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Treatments for Morton's neuroma
Barry G Matthews1, Colin E Thomson2, Michael P Harding3
1Faculty of Health, School of Clinical Sciences, Queensland University of Technology (QUT), Brisbane, Australia.
The Cochrane Database of Systematic Reviews
|February 9, 2024
Summary
Corticosteroid and local anaesthetic injections (CS+LA) show little difference in Morton
Area of Science:
- Podiatry and Neuropathy Research
- Evidence-Based Medicine and Clinical Trials
- Surgical and Non-Surgical Interventions
Background:
- Morton's neuroma (MN) is a painful neuropathy affecting the plantar digital nerve, commonly in the foot's third webspace.
- Symptoms include burning pain, shooting sensations, or feeling like walking on a pebble, significantly impacting quality of life and weight-bearing activities.
- Existing interventions for MN lack comprehensive evaluation through randomized controlled trials (RCTs).
Conclusions:
- Current evidence suggests CS+LA injections offer minimal benefit over LA for MN, with low certainty.
- Ultrasound guidance for CS+LA injections appears to offer probable benefits in pain reduction and functional improvement for MN patients.
- Future RCTs require improved methodology and optimal sample sizes to increase the certainty and precision of evidence regarding MN interventions.

