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Clinical-pathologic correlation: The impact of grossing at the bedside
C Alexis Noble1, Chinmoy Bhate2, Buu T Duong3
1PGY-3, Department of Dermatology, University of Mississippi Medical Center, Jackson, MS, United States.
Seminars in Diagnostic Pathology
|February 9, 2024
Summary
Clinicians must carefully select skin biopsy techniques, including anatomic site, biopsy type, and transport medium, for accurate pathology results. Proper specimen handling and detailed clinical information are essential for optimal diagnostic correlation.
Area of Science:
- Dermatopathology
- Surgical Pathology
Background:
- Accurate skin biopsy diagnosis relies on proper specimen handling.
- Clinicians may overlook critical factors in specimen submission, impacting results.
Purpose of the Study:
- To review the fundamentals of gross pathologic examination for skin biopsies.
- To emphasize the importance of clinician-pathologist collaboration for optimal diagnostic outcomes.
Main Methods:
- Review of basic gross pathologic examination principles.
- Presentation of four case examples illustrating clinical-pathologic correlation challenges.
Main Results:
- Optimal biopsy design includes appropriate anatomic location, biopsy type, depth, breadth, and transport medium.
- Accurate diagnostic interpretation necessitates complete clinical information on the requisition form.
- Proper grossing of tissue at the bedside is crucial.
Conclusions:
- Effective clinical-pathologic correlation requires clinicians to consider the pathologist's needs.
- Attention to biopsy technique and specimen submission enhances diagnostic accuracy.
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