Related Experiment Video

Updated: Jul 3, 2025

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
12:45

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing

Published on: December 11, 2017

10.5K

[Painful left bundle branch block]

János Tomcsányi1

  • 11 Betegápoló Irgalmasrend Budai Irgalmasrendi Kórháza, Kardiológia Budapest, Árpád fejedelem u. 7., 1023 Magyarország.

Orvosi Hetilap
|February 11, 2024
PubMed

Insights

A rare case of effort-induced angina linked to left bundle branch block in normal coronary arteries was successfully treated. Combined therapy with ivabradine and trimetazidine prevented recurrence of angina and left bundle branch block.

Area of Science:

  • Cardiology
  • Electrophysiology

Background:

  • Effort-induced angina typically suggests coronary artery disease.
  • Left bundle branch block (LBBB) can sometimes mimic cardiac symptoms.

Purpose of the Study:

  • To present a case of angina pectoris caused by frequency-dependent left bundle branch block in a patient with normal coronary arteries.
  • To discuss the potential pathomechanism and treatment of this condition.

Main Methods:

  • A case study involving a patient experiencing angina during exercise.
  • Electrocardiogram (ECG) monitoring during exercise stress testing.
  • Pharmacological intervention with ivabradine and trimetazidine.

Main Results:

  • Exercise triggered both angina pectoris and a complete left bundle branch block on ECG.
  • Symptoms and LBBB resolved upon cessation of exercise.
  • Combined treatment with ivabradine and trimetazidine prevented recurrence of angina and LBBB.

Conclusions:

  • Frequency-dependent left bundle branch block can present as exertional angina even with normal coronary arteries.
  • Combined therapy with ivabradine and trimetazidine may be an effective treatment option for this specific condition.

Keywords:
cardiac resynchronization therapyfájdalmas bal-Tawara-szár-blokkivabradinivabradinemicrovascular anginamicrovascularis anginapainful left bundle branch blockreszinkrón pacemakerterápiatrimetazidintrimetazidine

More Related Videos

Cox-Maze IV Procedure Concomitant with Valvular Surgery In Situs Inversus Dextrocardia: A Single-Center Experience in China08:42

Cox-Maze IV Procedure Concomitant with Valvular Surgery In Situs Inversus Dextrocardia: A Single-Center Experience in China

Published on: February 11, 2022

3.5K
A Large Animal Model for Pulmonary Hypertension and Right Ventricular Failure: Left Pulmonary Artery Ligation and Progressive Main Pulmonary Artery Banding in Sheep07:02

A Large Animal Model for Pulmonary Hypertension and Right Ventricular Failure: Left Pulmonary Artery Ligation and Progressive Main Pulmonary Artery Banding in Sheep

Published on: July 15, 2021

3.1K

Related Concept Videos

Cardiovascular System Abnormal Findings II: Auscultation01:25

Cardiovascular System Abnormal Findings II: Auscultation

Auscultation, an essential part of a heart examination, is done using a stethoscope. It provides crucial information about heart function and possible heart problems. Due to heart problems, abnormal sounds can be heard during systole or diastole. These sounds include S3 and S4 gallops, opening snaps, systolic clicks, and murmurs.
Abnormal Heart Sounds
Gallops:
149
Assessment of the Cardiovascular System III: Palpation01:27

Assessment of the Cardiovascular System III: Palpation

Palpation involves feeling the body to evaluate texture, size, consistency, and tenderness for assessing cardiovascular health. The following steps are organized in a head-to-toe order:
Jugular Venous Pressure (JVP) Measurement
Position the patient at a thirty- to forty-five-degree angle or in a semi-fowler's position. Look for the highest point of pulsation in the internal jugular vein and measure the vertical distance to the angle of Loius or sternal angle. A normal JVP is 3-4 cm above...
340
Cardiovascular System Abnormal Findings I: Inspection and Palpation01:29

Cardiovascular System Abnormal Findings I: Inspection and Palpation

In a cardiovascular examination, inspection and palpation are crucial for identifying abnormalities.
Abnormal findings observed during an inspection
399
Disturbances in Heart Rhythm01:28

Disturbances in Heart Rhythm

Arrhythmia or dysrhythmia refers to an abnormal heart rhythm caused by a defect in the heart's conduction system. It can cause the heart to beat irregularly, too quickly, or too slowly, leading to symptoms like chest pain, shortness of breath, and fainting. Factors such as stress, caffeine, alcohol, nicotine, cocaine, certain drugs, congenital defects, diseases, and electrolyte abnormalities can trigger arrhythmias.
Arrhythmias are categorized by their speed, rhythm, and origin. A slow...
957
Pulse amplitude and quality01:17

Pulse amplitude and quality

Pulse amplitude is a crucial indicator of cardiac health because it provides valuable insights into the strength of left ventricular contractions and the overall uniformity of blood circulation within the vasculature. The strength of the pulse is directly related to the force with which the heart contracts and the volume of blood being pumped.
A weak or absent pulse may indicate reduced cardiac output or poor left ventricular contraction, which can be signs of cardiovascular dysfunction or...
1.8K
Heart Valves01:16

Heart Valves

The human heart is a complex organ with an intricate system of valves that regulate blood flow. There are two main types of valves: atrioventricular (AV) valves and semilunar valves.
The AV valves prevent the backflow of blood from the ventricles to the atria during ventricular contraction. These valves function with the assistance of the chordae tendineae and papillary muscles. When the ventricles are relaxed, the chordae tendineae are slack, allowing blood to flow from the atria into the...
4.6K