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Low-grade fibromyxoid tumor of the dura: A new entity?
Mahlon Johnson1, Howard Silberstein2, David Korones3
1Department of Neuropathology, Children's Hospital of Los Angeles, University of Rochester School of Medicine, Rochester, United States.
Background:
Low-grade fibromyxoid tumors are uncommon in children. Their differentiation from high-grade fibromyxoid tumors, as seen in adults, is imperative to diagnosis. Awareness of the entity and its subsequent behavior may guide management and predict outcomes.
Case Description:
We describe the case of a previously unreported low-grade fibromyxoid tumor of the cerebellum in an 8-year-old male. Extensive immunohistochemical, next-generation sequencing, and attempted DNA methylation profiling are reported. There has been no recurrence during the 6-year follow-up. Screening excluded multiple myxoid tumors, including low-grade fibromyxoid sarcoma. The findings suggest that, with gross total resection, the lesions may not recur.
Conclusion:
The case of fibromyxoid tumor with 6-year follow-up and the limited literature of similar tumors are reviewed.
