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Nutritional interventions for preventing and treating pressure ulcers.

Gero Langer1, Ching Shan Wan2,3, Astrid Fink4

  • 1Institute of Health and Nursing Sciences, Martin Luther University Halle-Wittenberg, Halle (Saale), Germany.

The Cochrane Database of Systematic Reviews
|February 12, 2024
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Summary

Nutritional interventions show uncertain benefits for preventing and treating pressure ulcers. While some supplements may slightly improve healing, evidence remains limited, necessitating larger studies for clarity on nutritional support effectiveness.

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Area of Science:

  • Clinical Nutrition
  • Wound Healing
  • Gerontology

Background:

  • Pressure ulcers are common, painful skin injuries affecting vulnerable populations.
  • Nutritional optimization is key for pressure ulcer prevention and treatment.
  • Specific nutrient roles in pressure ulcer management require further investigation.

Purpose of the Study:

  • To evaluate the efficacy and safety of nutritional interventions for pressure ulcer prevention and treatment.
  • To compare various diets and supplements against standard diets or other nutritional approaches.

Main Methods:

  • Systematic review and meta-analysis of 33 randomized controlled trials (RCTs).
  • Included participants with or without existing pressure ulcers.
  • Assessed outcomes including ulcer incidence, healing rates, and side effects using GRADE criteria.

Main Results:

  • Nutritional interventions showed little to no difference in preventing pressure ulcers compared to standard diets.
  • Energy, protein, and micronutrient supplements may slightly increase pressure ulcer healing rates.
  • Evidence on specific nutrients (e.g., arginine, zinc) and side effects remains very uncertain.

Conclusions:

  • The benefits of nutritional interventions for pressure ulcers are largely uncertain.
  • Supplements may offer slight advantages in healing, but evidence is low to moderate certainty.
  • Larger, well-designed studies are needed to clarify the role of specific nutrients and diets.