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Updated: May 11, 2026

Transplantation of Pulmonary Valve Using a Mouse Model of Heterotopic Heart Transplantation
Published on: July 23, 2014
Transcatheter pulmonary valve replacement after pulmonary homograft dysfunction
Marie-Catherine Morgant1, Chloé Bernard2, Luc Lorgis3
1Department of Cardiovascular and Thoracic Surgery, Dijon University Hospital, Dijon, France - marie-catherine.morgant@chu-dijon.fr.
Pulmonary homograft dysfunction after a Ross procedure poses treatment challenges. Transcatheter pulmonary valve replacement offers a successful minimally invasive option for early stenosis.
Area of Science:
- Cardiology
- Cardiovascular Surgery
- Interventional Cardiology
Background:
- Pulmonary homograft dysfunction presents a significant clinical challenge, particularly in patients with prior Ross procedures.
- Reoperation for pulmonary homograft failure is associated with high morbidity and mortality rates.
Observation:
- A case of early, severe pulmonary homograft stenosis was identified 18 months post-Ross procedure.
Findings:
- Successful management of early severe pulmonary homograft stenosis was achieved using transcatheter pulmonary valve replacement (TPVR).
- TPVR provided a less invasive alternative to reoperation for this complex patient.
Implications:
- Transcatheter pulmonary valve replacement is a viable and effective treatment option for early pulmonary homograft stenosis following a Ross procedure.
- This approach may reduce the need for conventional reoperation, thereby improving patient outcomes and lowering healthcare costs.
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