Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Transducer Mechanism: Enzyme-Linked Receptors

Transducer Mechanism: Enzyme-Linked Receptors

Enzyme-linked receptors are cell-surface receptors acting as an enzyme or associating with an enzyme intracellularly. They make excellent drug targets. Drugs can bind to the extracellular ligand-binding domain or directly affect their enzymatic domain and alter their activity.
Major types that are helpful drug targets include:

Microbial Biosensors

Microbial Biosensors

Microbial biosensors are analytical devices that utilize living microbes to detect specific substances through measurable signals. These devices consist of two main components: biosensing organisms and signal-transducing elements. Biosensing organisms, such as Escherichia coli or Saccharomyces cerevisiae, are typically housed in multiwell plates connected to transducers, enabling rapid, real-time detection of target analytes.Signal Generation MechanismWhen a target analyte—such as...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Granular Hydrogel Composites for Noninvasive Optical Biosensing.

Journal of biomedical materials research. Part A·2026

Same author

Hemostatic B-knob-triggered microgels (BK-TriGs) to address bleeding in neonates.

Science advances·2026

Same author

Advances in Fibrin-Based Bioprinting for Skin Tissue Regeneration: Exploring Design, and Innovative Approaches.

Biomedical materials & devices (New York, N.Y.)·2026

Same author

Integrating the affinity and anion-exchange purification of AAV8: how the selective enrichment of full capsids at the affinity capture step enhances the downstream processing of gene therapies.

Journal of chromatography. A·2025

Same author

Affinity Peptides With pH Sensitivity for the Enrichment of CD38<sup>+</sup> Cells.

Biotechnology and bioengineering·2025

Same author

Development of an Extended Gate Field Effect Transistor Enzymatic Sensor to Monitor Glucose in Human Plasma.

Journal of diabetes science and technology·2025

Search research articles

Related Experiment Video

Updated: Jul 1, 2026

Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing

Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing

Published on: June 1, 2012

Insertable Biosensors: Combining Implanted Sensing Materials with Wearable Monitors.

David Chimene¹, Kirstie M K Queener², Brian S Ko¹

¹Department of Biomedical Engineering, Texas A&M University, College Station, Texas, USA;

Annual Review of Biomedical Engineering

|February 12, 2024

Summary

Insertable biosensor systems offer improved patient comfort and reduced risks compared to traditional devices. This review explores innovations and challenges for next-generation implantable biosensors for long-term health monitoring.

Keywords:

biosensors implantable insertable precision medicine wearables

More Related Videos

Chronic Implantation of Multiple Flexible Polymer Electrode Arrays

Chronic Implantation of Multiple Flexible Polymer Electrode Arrays

Published on: October 4, 2019

Conformable Wearable Electrodes: From Fabrication to Electrophysiological Assessment

Conformable Wearable Electrodes: From Fabrication to Electrophysiological Assessment

Published on: July 22, 2022

Related Experiment Videos

Last Updated: Jul 1, 2026

Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing

Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing

Published on: June 1, 2012

Chronic Implantation of Multiple Flexible Polymer Electrode Arrays

Chronic Implantation of Multiple Flexible Polymer Electrode Arrays

Published on: October 4, 2019

Conformable Wearable Electrodes: From Fabrication to Electrophysiological Assessment

Conformable Wearable Electrodes: From Fabrication to Electrophysiological Assessment

Published on: July 22, 2022

Area of Science:

Biomedical Engineering
Medical Diagnostics
Wearable Technology

Background:

Insertable biosensor systems comprise an implantable sensor and a wearable monitor.
They eliminate physical connections, offering advantages over percutaneous systems.
Key benefits include enhanced patient comfort and reduced infection risks.

Purpose of the Study:

To review key developments in insertable biosensor systems.
To highlight innovations in sensing, transduction, and communication.
To identify challenges for next-generation extended-use devices.

Main Methods:

Literature review of insertable biosensor system advancements.
Analysis of technical challenges and innovations.
Discussion of future needs for diagnostic and prognostic devices.

Main Results:

Insertable biosensors enable remote monitoring without physical connections.
Innovations are addressing challenges in sensing, transduction, and communication.
These systems show promise for longitudinal biometric monitoring.

Conclusions:

Insertable biosensor systems represent a promising advancement in medical diagnostics.
Overcoming technical hurdles is crucial for realizing their full potential.
Further development is needed for extended-use diagnostic and prognostic applications.