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Related Concept Videos

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Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
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Quantifying Cognitive Decrements Caused by Cranial Radiotherapy
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Comorbid Dementia and Cancer Therapy Decision-Making: A Scoping Review.

Sean N Halpin1, Gabriel Alain2, Aaron Seaman3

  • 1GenOmics and Translational Research Center RTI International, Research Triangle Park, NC, USA.

Journal of Applied Gerontology : the Official Journal of the Southern Gerontological Society
|February 13, 2024
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Navigating cancer therapy for older adults with dementia requires clear communication. This review highlights challenges and emphasizes patient-centered decisions for people living with dementia (PLWD) and their caregivers.

Keywords:
cancerdecision-makingdementiahealth communicationscoping review

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Area of Science:

  • Geriatric Oncology
  • Neuroscience
  • Clinical Decision-Making

Background:

  • Comorbid dementia presents significant challenges in cancer therapy decision-making for older adults.
  • Existing literature on this complex intersection is synthesized to identify key issues.

Purpose of the Study:

  • To review recent (<5 years) literature on challenges in cancer therapy decision-making for older people living with dementia (PLWD) and their caregivers.
  • To identify strategies for improving the decision-making process.

Main Methods:

  • Systematic literature search yielding 20,763 references.
  • Screening of 8,767 titles and abstracts.
  • Inclusion of eight studies (six qualitative, one mixed-methods, one quasi-experimental).

Main Results:

  • Most studies were from the UK, focusing on breast and prostate cancers.
  • Communication between patients, caregivers, and clinical teams can reduce stress and address ethical concerns.
  • Dementia type and stage were variably reported across studies.

Conclusions:

  • Enhanced communication is crucial for patient-centered cancer therapy decisions in older PLWD.
  • Findings can inform clinicians, caregivers, and patients facing these complex choices.
  • Further research may benefit from more diverse geographical and demographic reporting.