Related Experiment Video

Updated: May 12, 2026

Isolation of Distinct Cell Populations from the Developing Cerebellum by Microdissection
08:02

Isolation of Distinct Cell Populations from the Developing Cerebellum by Microdissection

Published on: September 21, 2014

9.6K

Long interspersed nuclear elements safeguard neural progenitors from precocious differentiation

Tomohisa Toda1, Tracy A Bedrosian2, Simon T Schafer3

  • 1Laboratory of Genetics, The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA; Laboratory of Neural Epigenomics, Institute of Medical Physics and Micro-tissue Engineering, Friedrich-Alexander-Universität Erlangen-Nürnberg, 91054 Erlangen, Germany; Nuclear Architecture in Neural Plasticity and Aging Laboratory, German Center for Neurodegenerative Diseases, 01307 Dresden, Germany.

Cell Reports
|February 13, 2024
PubMed

Keywords:
CP: Developmental biologyCP: NeuroscienceL1LINE-1brain developmentneural progenitor cellsrepetitive elements

More Related Videos

Assessing Primary Neurogenesis in Xenopus Embryos Using Immunostaining06:47

Assessing Primary Neurogenesis in Xenopus Embryos Using Immunostaining

Published on: April 12, 2016

9.6K
Homochronic Transplantation of Interneuron Precursors into Early Postnatal Mouse Brains10:08

Homochronic Transplantation of Interneuron Precursors into Early Postnatal Mouse Brains

Published on: June 8, 2018

7.9K

Related Concept Videos

Determination01:51

Determination

During embryogenesis, cells become progressively committed to different fates through a two-step process: specification followed by determination. Specification is demonstrated by removing a segment of an early embryo, “neutrally” culturing the tissue in vitro—for example, in a petri dish with simple medium—and then observing the derivatives. If the cultured region gives rise to cell types that it would normally generate in the embryo, this means that it is specified. In contrast, determination...
Maintenance of the ES Cell State01:14

Maintenance of the ES Cell State

The cells of the blastocyst inner cell mass only remain pluripotent for a short time. This state of pluripotency and self-renewal can be maintained in embryonic stem (ES) cell culture by adding specific chemicals or growth factors to ensure the cells can continue dividing and later differentiate into different cell types. In some cases, the cells are grown on a feeder layer of differentiated cells, which provides the growth factors and extracellular matrix components necessary for stem cell...