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Updated: Jul 3, 2025

Integration of Wet and Dry Bench Processes Optimizes Targeted Next-generation Sequencing of Low-quality and Low-quantity Tumor Biopsies
Published on: April 11, 2016
Envision the future of precision medicine in pediatric cancer
1Cancer and Blood Diseases Institute, Department of Pediatrics, Children's Hospital Los Angeles, Los Angeles, CA 90027, USA; University of Southern California, Los Angeles, CA 90027, USA.
Abstract:
Exploring the diversity within the tumor microenvironment (TME) can offer crucial insights to steer cancer therapy toward precision medicine. In this issue of Cancer Cell, Wienke et al. undertake a comprehensive single-cell analysis of neuroblastoma, unveiling its immune landscape and identifying NECTIN2-TIGIT as a promising target for immunotherapy.
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