Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Bacterial Signaling01:30

Bacterial Signaling

32.1K
Bacterial signaling can occur within bacteria (intracellular) or between bacteria (intercellular). At times, a group of bacteria behaves like a community. To achieve this, they engage in quorum sensing, the perception of higher cell density that causes changes in gene expression. Quorum sensing involves both extracellular and intracellular signaling. The signaling cascade starts with a molecule called an autoinducer (AI). Individual bacteria produce AIs that move out of the bacterial cell...
32.1K
Types of RNA01:23

Types of RNA

63.7K
Overview
Three main types of RNA are involved in protein synthesis: messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA). These RNAs perform diverse functions and can be broadly classified as protein-coding or non-coding RNA. Non-coding RNAs play important roles in the regulation of gene expression in response to developmental and environmental changes. Non-coding RNAs in prokaryotes can be manipulated to develop more effective antibacterial drugs for human or animal use.
RNA...
63.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

High-Performance Prevascularized SHED-Laden rGO@Hydrogel Achieves Optimized Diabetic Bone Defect Repair.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026
Same author

Soluble Sema4D From γδ T Cells Exerts Osteoblast Inhibition via Plexin-B/mTOR Signalling Contributing to Pathogenesis of Bisphosphonate-Related Osteonecrosis of the Jaws.

Cell proliferation·2025
Same author

Nanographene Oxide Promotes Angiogenesis by Regulating Osteoclast Differentiation and Platelet-Derived Growth Factor Secretion.

ACS nano·2024
Same author

Novel Carbon Quantum Dots Precisely Trigger Ferroptosis in Cancer Cells through Antioxidant Inhibition Synergistic Nanocatalytic Activity.

ACS applied materials & interfaces·2024
Same author

Biomimetic Hydrogels as the Inductive Endochondral Ossification Template for Promoting Bone Regeneration.

Advanced healthcare materials·2023
Same author

GeO<sub>2</sub> Nanoparticles Decorated in Amorphous Carbon Nanofiber Framework as Highly Reversible Lithium Storage Anode.

Molecules (Basel, Switzerland)·2023

Related Experiment Video

Updated: Jul 3, 2025

Anti-virulent Disruption of Pathogenic Biofilms using Engineered Quorum-quenching Lactonases
07:47

Anti-virulent Disruption of Pathogenic Biofilms using Engineered Quorum-quenching Lactonases

Published on: January 1, 2016

11.6K

Nanomaterials Regulate Bacterial Quorum Sensing: Applications, Mechanisms, and Optimization Strategies.

Chen Hu1, Guixin He1, Yujun Yang1

  • 1Stomatological Hospital, School of Stomatology, Southern Medical University, Guangzhou, 510280, China.

Advanced Science (Weinheim, Baden-Wurttemberg, Germany)
|February 13, 2024
PubMed
Summary

Nanomaterials offer a promising approach to combat bacterial resistance by disrupting bacterial communication (quorum sensing, QS). This review details how nanomaterials regulate QS at different stages, guiding the development of advanced anti-virulence therapies.

Keywords:
antibacterialanti‐virulence therapydrug resistancenanomaterialsoptimization strategiesquorum sensing

More Related Videos

Solubilization and Bio-conjugation of Quantum Dots and Bacterial Toxicity Assays by Growth Curve and Plate Count
13:06

Solubilization and Bio-conjugation of Quantum Dots and Bacterial Toxicity Assays by Growth Curve and Plate Count

Published on: July 11, 2012

14.4K
Author Spotlight: Advancing Therapeutics to Treat Vibriosis in Humans and Aquatic Organisms
03:29

Author Spotlight: Advancing Therapeutics to Treat Vibriosis in Humans and Aquatic Organisms

Published on: May 31, 2024

463

Related Experiment Videos

Last Updated: Jul 3, 2025

Anti-virulent Disruption of Pathogenic Biofilms using Engineered Quorum-quenching Lactonases
07:47

Anti-virulent Disruption of Pathogenic Biofilms using Engineered Quorum-quenching Lactonases

Published on: January 1, 2016

11.6K
Solubilization and Bio-conjugation of Quantum Dots and Bacterial Toxicity Assays by Growth Curve and Plate Count
13:06

Solubilization and Bio-conjugation of Quantum Dots and Bacterial Toxicity Assays by Growth Curve and Plate Count

Published on: July 11, 2012

14.4K
Author Spotlight: Advancing Therapeutics to Treat Vibriosis in Humans and Aquatic Organisms
03:29

Author Spotlight: Advancing Therapeutics to Treat Vibriosis in Humans and Aquatic Organisms

Published on: May 31, 2024

463

Area of Science:

  • Biotechnology
  • Materials Science
  • Microbiology

Background:

  • Bacterial communication, known as quorum sensing (QS), is a key target for anti-virulence strategies to overcome antibiotic resistance.
  • Nanomaterials are increasingly explored for regulating QS due to their unique properties and design flexibility.

Purpose of the Study:

  • To review the mechanisms by which nanomaterials regulate bacterial QS processes.
  • To identify key factors influencing nanomaterial-mediated QS regulation.
  • To summarize optimization strategies for enhancing QS regulatory activity.

Main Methods:

  • Focuses on reviewing existing literature on nanomaterial interactions with bacterial QS.
  • Analyzes QS regulation mechanisms in signal supply and signal transduction.
  • Considers the influence of nanomaterial properties and environmental factors.

Main Results:

  • Nanomaterials can modulate bacterial QS at various steps, including signal synthesis, secretion, accumulation, perception, and response.
  • Both intrinsic nanomaterial characteristics and environmental conditions significantly impact QS regulation efficacy.
  • Specific optimization strategies can enhance the performance of nanomaterials in QS-based anti-virulence approaches.

Conclusions:

  • Regulating bacterial QS with nanomaterials is a viable strategy for developing novel anti-virulence therapies.
  • Understanding the detailed mechanisms of nanomaterial-QS interactions is crucial for designing improved nanomaterials.
  • This review provides a foundation for future research in nanomaterial-based anti-virulence applications.