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Author Spotlight: Methodologies and Advancements of Chronic Pain Management Research
Published on: January 5, 2024
[Psychedelics in the field of chronic pain. A path to explore?]
Aude Molinard-Chenu1,2, Georgios Tsimploulis3, Louise Penzenstadler4
1Service de psychiatrie de liaison et d'intervention de crise, Département de psychiatrie, Hôpitaux universitaires de Genève, 1211 Genève 14.
Abstract:
Psychedelics are emerging as a therapeutic innovation in psychiatry and their use in chronic pain is worth exploring. In fact, they can modulate the serotonergic system, affecting central pain sensitization mechanisms. Ketamine, used for chronic analgesia, can lead to pain reduction, but additional studies are needed to assess its longterm effectiveness. "Classic" psychedelics are recently attracting renewed interest for their potential effects on chronic pain. Despite limited studies, evidence suggests analgesic benefits, an effect on inflammation, and potential impacts on certain functional disorders. These results pave the way for further research in this ever-evolving field.
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