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Related Experiment Video

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Assessment of Neuromuscular Function Using Percutaneous Electrical Nerve Stimulation
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Evaluating peripheral neuromuscular function with brief movement-evoked pain.

Emmanuel Ogalo1,2, Lukas D Linde1, Hannah Ro1

  • 1International Collaboration on Repair Discoveries (ICORD), Vancouver, British Columbia, Canada.

Journal of Neurophysiology
|February 14, 2024
PubMed
Summary

Movement-evoked pain reduces peak force and rate of force development in healthy adults, despite unchanged muscle activity. This suggests altered neuromuscular strategies rather than reduced muscle activation during painful movements.

Keywords:
electromyographyfirst dorsal interosseousforce developmentmovement-evoked painneuromuscular adaptation

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Area of Science:

  • Neuromuscular physiology
  • Pain science
  • Musculoskeletal health

Background:

  • Movement-evoked pain is a common yet understudied cause of disability in musculoskeletal conditions.
  • Understanding the neuromuscular response to movement pain is crucial for developing effective interventions.

Purpose of the Study:

  • To investigate the impact of movement-evoked pain on force production, electromyographic (EMG) activity, and rate of force development (RFD) during submaximal contractions.
  • To explore potential neuromuscular adaptations underlying force reduction during pain.

Main Methods:

  • Healthy adults performed isometric first finger abduction contractions under baseline (pain-free) and experimentally induced movement-evoked pain conditions.
  • Laser stimulation was used to induce pain on the dorsum of the hand.
  • Force, EMG, and RFD were measured during submaximal contractions.

Main Results:

  • Movement-evoked pain significantly decreased normalized force (11%) and RFD (15%) compared to baseline.
  • No significant changes were observed in normalized peak EMG activity.
  • Early measures of RFD and EMG within 50-200 ms of movement onset remained unaffected.

Conclusions:

  • Movement-evoked pain impairs peak force and RFD, but not early contractile properties or overall muscle activation (EMG).
  • Findings suggest a reorganization of motoneuronal activation strategies or increased antagonist coactivation may explain reduced force output.
  • These neurophysiological changes highlight potential mechanisms contributing to disability in movement-evoked pain conditions.