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[Autoinflammatory diseases in children: The contribution of genetics]
Guilaine Boursier1, Isabelle Touitou1
1Laboratoire de génétique des maladies rares et auto-inflammatoires, centre de référence des maladies auto-inflammatoires rares et des amyloses (CeRéMAIA), CHU de Montpellier, université de Montpellier, Inserm 1183, France.
Autoinflammatory Diseases In Children:
THE CONTRIBUTION OF GENETICS. Autoinflammatory diseases (AIDs) have benefited from modern genetic tools, in particular the widespread use of high-throughput sequencing, which has helped to improve our knowledge of the inheritance patterns of AIDs, whether hereditary or multifactorial. The case for genetic testing has become compelling. However, the new modes of inheritance revealed in recent years complicate genetic counselling and justify close collaboration between clinicians and biologists during multidisciplinary clinical meetings.
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