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Related Experiment Video

Updated: Jul 3, 2025

Immunohistochemistry and Multiple Labeling with Antibodies from the Same Host Species to Study Adult Hippocampal Neurogenesis

Immunohistochemistry and Multiple Labeling with Antibodies from the Same Host Species to Study Adult Hippocampal Neurogenesis

Published on: April 22, 2015

Timing neurogenesis: a clock or an algorithm?

Julien Pigeon¹, Bassem A Hassan¹

¹Institut du Cerveau-Paris Brain Institute (ICM), Sorbonne Université, Inserm, CNRS, Hôpital Pitié-Salpêtrière, Paris, France.

Current Opinion in Genetics & Development

|February 14, 2024

Summary

This summary is machine-generated.

Molecular mechanisms control timing in neurogenesis, driven by evolutionary selection. A computer science framework aids understanding of these brain development processes.

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Last Updated: Jul 3, 2025

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Published on: December 11, 2010

Area of Science:

Neuroscience
Evolutionary Biology
Developmental Biology

Background:

Neurogenesis timing is crucial for proper brain development.
Molecular mechanisms controlling this timing are increasingly recognized.
Evolutionary pressures likely shaped these temporal control systems.

Purpose of the Study:

To review molecular mechanisms controlling neurogenesis timing.
To introduce a computer science-inspired conceptual framework.
To discuss the role of these mechanisms in brain development and evolution.

Main Methods:

Literature review of molecular mechanisms in neurogenesis.
Conceptual analysis using a computer science framework.
Discussion of evolutionary implications.

Main Results:

Several molecular mechanisms contribute to precise temporal control during neurogenesis.
A computational framework offers new perspectives on these biological processes.
These mechanisms are subject to evolutionary selection.

Conclusions:

Understanding the temporal control of neurogenesis is vital for developmental neuroscience.
A computer science perspective can illuminate the complexity of these biological timing systems.
Evolutionary insights are key to deciphering the origins of neurogenesis timing.