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Updated: Jul 3, 2025

Resurrection of Dormant Daphnia magna: Protocol and Applications
Published on: January 19, 2018
The diversity, destiny, and memory of DAMs
1Brain Immunology and Glia Center, University of Virginia, Charlottesville, VA, USA; Department of Neuroscience, University of Virginia, Charlottesville, VA, USA.
Abstract:
Disease-associated microglia (DAMs) are a unique microglial state in development and various CNS pathologies. In this issue of Immunity, Lan and colleagues provide novel insights into the diversity of DAMs in CNS diseases, revealing their terminal fate following juvenile stroke verses their reversible fate following neonatal stroke and their ability to maintain immune memory upon return to homeostatic states.
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