Antithrombotic Treatment for Chronic Coronary Syndrome: Evidence and Future Perspectives

Area of Science:

• Cardiology
• Vascular Medicine
• Pharmacology

Background:

• Coronary artery disease (CAD) presents diversely, from asymptomatic cases to acute coronary syndrome.
• Chronic coronary syndrome (CCS) is prevalent, necessitating robust secondary prevention strategies to avert ischemic events.

Purpose of the Study:

• To review current antithrombotic treatment strategies for patients with chronic coronary syndrome.
• To summarize key guideline recommendations and offer insights into future long-term antithrombotic approaches.

Main Methods:

• This is a review article.
• It synthesizes current guidelines and literature on antithrombotic therapy in CCS.
• It discusses patient-specific factors, comorbidities, and revascularization methods influencing treatment choices.

Main Results:

• Antithrombotic therapy is crucial for secondary prevention in CCS.
• Dual antiplatelet therapy is standard post-stent implantation.
• Antiplatelet monotherapy is used for long-term prevention, while oral anticoagulation is reserved for specific indications like atrial fibrillation.

Conclusions:

• Antithrombotic therapy selection in CCS is individualized based on clinical factors and interventions.
• Guideline-based strategies ensure optimal secondary prevention.
• Future research will likely focus on refining long-term antithrombotic regimens for CCS patients.