Related Experiment Video
Updated: Jul 3, 2025

Visualizing Lung Cellular Adaptations during Combined Ozone and LPS Induced Murine Acute Lung Injury
Published on: March 21, 2021
Acute occupational inhalation injuries-United States, 2011-2022
Nirmala T Myers1, Katelynn E Dodd1, Janet M Hale1
1Respiratory Health Division, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, Morgantown, West Virginia, USA.
Acute chemical inhalation injuries are preventable. This study identified inorganic gases and manufacturing/construction sectors as key risks for US workers, highlighting the need for targeted prevention strategies.
Area of Science:
- Occupational Health
- Environmental Health
- Toxicology
Background:
- Acute chemical inhalation injuries in the workplace are a significant concern.
- Existing national surveillance for these exposures is limited.
- This study aims to identify common acute inhalation exposure incidents by industry sector.
Purpose of the Study:
- To characterize inhalation-related injuries and exposures among US workers.
- To identify industry-specific trends in acute inhalation incidents.
- To inform prevention strategies for occupational chemical exposures.
Main Methods:
- Analysis of state and federal records from the Occupational Safety and Health Administration (OSHA) Occupational Safety and Health Information System (OIS) accident database.
- Data collected from April 2011 to March 2022.
- Calculation of industry-specific injury, hospitalization, and fatality rates.
Main Results:
- Inorganic gases (e.g., carbon monoxide) were the most frequent cause of acute inhalation incidents (52.9%).
- Acids, bases, and oxidizing agents (e.g., anhydrous ammonia) accounted for 12.9% of incidents.
- Manufacturing (28.6%) and construction (17.2%) sectors reported the highest number of fatal and nonfatal injuries.
Conclusions:
- Acute inhalation exposures affect workers across most industries.
- Surveillance data can guide employers in recognizing and preventing common exposures, such as inorganic gases in manufacturing.
- Worker training on exposure risks, health effects, and protective equipment is crucial for preventing inhalation injuries.
Related Concept Videos
Inhalational Anesthetics: Overview
Acute Respiratory Failure-I
Definition: It is defined by specific criteria based on blood gas measurements. Hypoxemia happens when the partial pressure of oxygen (PaO2) falls below 60 mmHg. At the same time,...
Pulmonary Cycle: Exhalation
Acute Respiratory Failure-II
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
Inhaled Medications
Pneumonia I: Introduction
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...

