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Extra-ocular sebaceous carcinoma - A rare case report
Manda Sindhura1, Tummidi Santosh2, Jarang Rajesh Kumar3
1Department of Pathology, AIIMS, Mangalagiri, Andhra Pradesh, India.
Indian Journal of Pathology & Microbiology
|February 15, 2024
Summary
Sebaceous gland carcinoma, a rare skin cancer, can present as a rapidly growing back swelling. Early misdiagnosis as a cyst delays treatment, increasing patient risk.
Area of Science:
- Dermatology
- Oncology
- Pathology
Background:
- Sebaceous gland carcinoma is a rare, aggressive skin malignancy originating from sebaceous glands.
- It occurs in ocular and extra-ocular locations, with ocular sites accounting for 75% of cases.
Observation:
- A 45-year-old female presented with a rapidly growing upper back swelling, initially misdiagnosed as an infected sebaceous cyst.
- Histopathology confirmed sebaceous carcinoma, Grade II, Stage P T3 Nx, with positive epithelial membrane antigen staining.
Findings:
- Sebaceous carcinoma incidence is low, estimated at 1-2 per million individuals annually, comprising 0.2-4.6% of all cutaneous neoplasms.
- Tumors often present as painless subcutaneous nodules but can mimic benign conditions, delaying diagnosis.
Implications:
- Misinterpretation as benign lesions leads to delayed diagnosis and inappropriate treatment.
- Timely and accurate diagnosis is crucial for managing this aggressive skin cancer and improving patient outcomes.
