Related Experiment Video
Updated: Jul 3, 2025

Neisseria meningitidis Infection of Induced Pluripotent Stem-Cell Derived Brain Endothelial Cells
Published on: July 14, 2020
Twins with meningitis due to Neisseria meningitidis
Gülsüm İclal Bayhan1, Saliha Kanık Yüksek2, Latife Güder2
1MD, Ankara Yıldırım Beyazıt University, Faculty of Medicine, and Ankara City Hospital, Department of Pediatric Infectious Disease, Üniversiteler Mahallesi, Bilkent Caddesi, Çankaya, Ankara, Turkey.
Introduction:
The incidence of invasive meningococcal disease is highest in infants and young children.
Case Report:
Twin infants diagnosed two days apart with meningitis due to N. meningitidis serogroup B are presented.
Conclusions:
There has never been a report of concurrent meningococcal meningitis in twin brothers. We wanted to highlight the high likelihood of meningococcal transmission through household contacts and the importance of antibiotic prophylaxis and meningococcal vaccination recommendations for close contacts of these cases.
Insights
Concurrent meningococcal meningitis occurred in twin infants. This case highlights the risk of household transmission and the need for prophylaxis and vaccination for close contacts.
Area of Science:
- Pediatrics
- Infectious Diseases
- Epidemiology
Background:
- Invasive meningococcal disease (IMD) disproportionately affects infants and young children.
- Neisseria meningitidis (N. meningitidis) is a leading cause of bacterial meningitis.
Observation:
- A case report details twin infants diagnosed with N. meningitidis serogroup B meningitis within a two-day interval.
- This represents the first reported instance of concurrent meningococcal meningitis in twin brothers.
Findings:
- The concurrent diagnosis in twins suggests a high probability of meningococcal transmission within household contacts.
- Early diagnosis and intervention are crucial for managing meningococcal meningitis.
Implications:
- Emphasizes the importance of antibiotic prophylaxis for close contacts of IMD cases.
- Highlights the critical role of meningococcal vaccination in preventing disease spread, especially in vulnerable populations.
- Underscores the need for heightened awareness and prompt medical evaluation for meningitis symptoms in young children and close contacts.
Related Concept Videos
Tonsillitis I: Introduction
Etiology
Three primary contributing factors have been identified.
Pneumonia I: Introduction
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Neurulation
Tonsillitis II: Management
Pneumonia III: Complications and Assessment

