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Updated: Jul 3, 2025

An In vitro System to Gauge the Thrombolytic Efficacy of Histotripsy and a Lytic Drug
Published on: June 4, 2021
Mechanical Tricuspid Valve Thrombosis Successfully Treated With Tissue Plasminogen Activator
Rebecca Haraf1,2, Tamara Atkinson1, Dai-Trang Elizabeth Le1
1Department of Cardiology, VA Portland Health Care System, Portland, Oregon, USA.
Abstract:
Prosthetic mechanical valve thrombosis has traditionally been managed with urgent surgical intervention. However, the risk of redo sternotomy can be prohibitively high in some patients. Thrombolytic therapy as a noninvasive treatment of mechanical valve thrombosis is a well-recognized alternative, but optimal dosing and patient selection remain incompletely characterized for right-side mechanical valves.
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