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Published on: October 13, 2023
Clinical Characterization and Ancillary Tests in Susac Syndrome: A Systematic Review
Adi Wilf-Yarkoni1, Ofir Zmira1, Assaf Tolkovsky1
1From the Departmet of Neurology (A.W.-Y., A.T.), Rabin Medical Center, Petah Tikva; Department of Neurology and Neurosurgery (A.W.-Y., A.T., B.P., S.G.G.), Sackler Faculty of Medicine, Tel Aviv University; Department of Neurology (O.Z.), Hillel Yaffe Medical Center, Hadera; Department of Neurology (O.Z.), Ruth and Bruce Rappaport Faculty of Medicine, Technion Institute of Technology, Haifa; Department of Neurology (B.P., S.G.G.), Sheba Medical Center, Ramat Gan, Israel; Department of Neurology (I.K.), University Hospital Knappschaftskrankenhaus Bochum, Ruhr University Bochum; Experimental and Clinical Research Center (F.P., J.D.), Max Delbrueck Center for Molecular Medicine and Charité Universitaetsmedizin Berlin; and Multiple Sclerosis Center (J.D.), Neurology Department, Oberhavel Kliniken, Hennigsdorf, Germany.
Susac syndrome (SuS), a rare microangiopathic disease, presents with encephalopathy, vision loss, and hearing loss. This study updates its features and diagnostic tools using cases from 2013-2022.
Area of Science:
- Neurology
- Ophthalmology
- Otolaryngology
- Rare Diseases
Background:
- Susac syndrome (SuS) is a rare microangiopathic condition.
- Previous reviews established understanding and diagnostic criteria by 2016.
- New cases and diagnostic advancements necessitate an update.
Conclusions:
- The study provides an updated profile of Susac syndrome.
- Revised diagnostic approaches are highlighted.
- Early diagnosis and treatment of SuS are emphasized.
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