Related Experiment Video
Updated: Jul 2, 2025
19:57
An Affordable HIV-1 Drug Resistance Monitoring Method for Resource Limited Settings
Published on: March 30, 2014
18.5K
A Community Guide Systematic Review: Digital HIV Pre-Exposure Prophylaxis Interventions
Emiko Kamitani1, Yinan Peng2, David Hopkins2
1Division of HIV Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, & TB Prevention, the Centers for Disease Control and Prevention (CDC), Atlanta, GA 30329-4027.
American Journal of Preventive Medicine
|February 17, 2024
Summary
Digital health tools effectively improve pre-exposure prophylaxis (PrEP) adherence among men who have sex with men, supporting HIV prevention efforts. These interventions show promise for increasing PrEP use and retention in care.
Area of Science:
- Public Health
- Digital Health Interventions
- HIV Prevention
Background:
- Pre-exposure prophylaxis (PrEP) is highly effective for HIV prevention when used consistently.
- Digital health interventions show promise for improving adherence to antiretroviral therapy.
- Evidence for digital PrEP adherence interventions among individuals without HIV is limited.
Purpose of the Study:
- To systematically review the characteristics and effectiveness of digital health interventions designed to improve PrEP adherence.
- To inform recommendations for digital interventions aimed at increasing PrEP use.
Main Methods:
- Systematic search of the CDC HIV Prevention Research Synthesis database (2000-2022).
- Inclusion of studies with comparison arms or pre-post data from high-income countries.
- Independent screening, data extraction, and risk of bias assessment by two reviewers.
Main Results:
- Nine studies were included, all focusing on gay, bisexual, and other men who have sex with men (MSM).
- All studies demonstrated improved PrEP adherence in intervention groups compared to controls or baseline.
- One study reported enhanced retention in PrEP care.
Conclusions:
- Digital health interventions utilizing various strategies can improve PrEP adherence and related outcomes.
- The findings support the Community Preventive Services Task Force recommendation for using these interventions to enhance PrEP adherence.
- Further research is needed due to the limited number of studies identified.
Related Concept Videos
01:10Retrovirus Life Cycles
46.0K
Retroviruses have a single-stranded RNA genome that undergoes a special form of replication. Once the retrovirus has entered the host cell, an enzyme called reverse transcriptase synthesizes double-stranded DNA from the retroviral RNA genome. This DNA copy of the genome is then integrated into the host’s genome inside the nucleus via an enzyme called integrase. Consequently, the retroviral genome is transcribed into RNA whenever the host’s genome is transcribed, allowing the...
46.0K
01:26Sexually Transmitted Infections
308
Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
308