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[Quantitative evaluation of various cardiac diseases using body surface mapping]
Insights
Body surface mapping effectively quantifies cardiac diseases. For anterior myocardial infarction, specific mapping parameters accurately assessed infarct size and ventricular function, correlating well with established diagnostic methods.
Area of Science:
- Cardiology
- Biomedical Engineering
- Medical Imaging
Context:
- Body surface mapping (BSM) is a non-invasive technique for quantitative cardiac electrical activity assessment.
- Evaluating cardiac diseases requires accurate methods to determine infarct size and ventricular function.
- Previous studies have explored BSM for various cardiac conditions.
Purpose:
- To quantitatively evaluate cardiac diseases using body surface mapping.
- To compare BSM parameters with established methods for assessing infarct size in anterior myocardial infarction (AMI).
- To correlate BSM parameters with left ventricular dimensions in aortic regurgitation (AR).
Summary:
- In 30 AMI cases, BSM parameters like nSubtraction 40 (sigma Subtr. 40) showed strong correlation with left ventricular (LV) asynergy (r=0.70).
- nSubtraction 10-60 (sigma Subtr. 10-60) correlated highly with ejection fraction (EF) (r=0.83) and 201Tl defect size (r=0.85).
- In 19 AR cases, BSM voltages were compared with LV diastolic dimension (LVDd) from echocardiography.
Impact:
- BSM provides a quantitative, non-invasive tool for assessing myocardial infarction severity.
- This technique offers potential for improved diagnosis and management of cardiac diseases.
- BSM parameters demonstrate significant correlation with established clinical and imaging metrics.
Abstract:
Body surface mapping (map) was used to evaluate various cardiac diseases quantitatively. For 30 cases with old anterior myocardial infarction (AMI), map parameters were compared with infarct size assessed by left ventriculography and 201Tl myocardial scintigraphy (LV% asynergy and 201Tl% defect, respectively). Parameters used in the present study were nSubtraction 40 (sigma Subtr. 40), which were obtained by the summation of voltages less than the lower limit of normal range (mean--2SD) at 40 msec from the QRS onset and nSubtraction 10-60 (sigma Subtr. 10-60), which was obtained by the integral of voltages below the normal range, calculated each 10 msec to 60 msec, as well as the number of lead points with Q waves of 30, 40 msec duration (nQ30, nQ40), and the summation of R voltages over the entire body surface (sigma R). In 19 cases with aortic regurgitation (AR), R and S voltages in each lead were compared with left ventricular diastolic dimension (LVDd) obtained by echocardiography. In 43 healthy persons and two patients with RV pacing, the ventricular activation time was measured in each lead (VAT map). In AMI, nSubtr. 40 correlated best with LV% asynergy (r = 0.70, p less than 0.001). EF and 201Tl% defect were related to nSubtr. 10-60 (r = 0.83, p less than 0.001 and r = 0.85, p less than 0.001, respectively).(ABSTRACT TRUNCATED AT 250 WORDS)