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Author Spotlight: Oral Candida Diagnosis to Advance Clinical Treatment Regimen for pSS Patients
Published on: March 1, 2024
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Oro-Pharyngeal Candidiasis in Two Dengue Patients
Drupad Das1, Shiv N Sahu1, Prasan K Panda1
1Internal Medicine, All India Institute of Medical Sciences, Rishikesh, Rishikesh, IND.
Cureus
|February 20, 2024
Summary
This study reports the first cases of oral candidiasis in severe dengue patients in India. These findings highlight the importance of monitoring for fungal infections during dengue recovery.
Area of Science:
- Infectious Diseases
- Mycology
Background:
- Dengue fever is a significant arboviral disease with increasing incidence in India.
- Oral candidiasis is a fungal infection rarely associated with dengue.
Observation:
- Two severe dengue cases presented with oral/oro-pharyngeal pseudomembranous candidiasis.
- Case 1: Young male, no comorbidities, presented with dengue, leukopenia, thrombocytopenia, hepatic involvement, and candidiasis.
- Case 2: Middle-aged male, smoker with diabetes, presented with dengue NS1 positivity, thrombocytopenia, hepatic involvement, and candidiasis.
Findings:
- Both patients experienced improvement with conservative management and oral nystatin.
- This suggests a potential link between severe dengue and secondary Candida infections.
Implications:
- Highlights the need to consider superadded fungal infections in dengue patients.
- Emphasizes the importance of clinical vigilance and further research into dengue-associated candidiasis.
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