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Updated: Jul 2, 2025

Multimodal 3D Printing of Phantoms to Simulate Biological Tissue

Multimodal 3D Printing of Phantoms to Simulate Biological Tissue

Published on: January 11, 2020

High-Throughput Two-Photon 3D Printing Enabled by Holographic Multi-Foci High-Speed Scanning.

Leran Zhang¹, Chaowei Wang¹, Chenchu Zhang²

¹CAS Key Laboratory of Mechanical Behavior and Design of Materials, Department of Precision Machinery and Precision Instrumentation, University of Science and Technology of China, Hefei 230026, China.

|February 20, 2024

Summary

This summary is machine-generated.

This study introduces a new two-photon polymerization (TPP) platform for faster 3D printing. It achieves high speed and resolution by using galvanometric mirrors and a liquid crystal on silicon spatial light modulator (LCoS-SLM) for parallel processing.

Keywords:

femtosecond laser functional microstructure high-throughput 3D printing holographic multifoci parallel processing

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Evaluation and Manipulation of Neural Activity Using Two-Photon Holographic Microscopy

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Published on: September 16, 2022

Area of Science:

Additive Manufacturing
Microfabrication
Optical Engineering

Background:

Two-photon polymerization (TPP) is a key technique for high-resolution 3D micro/nano additive manufacturing.
Current TPP methods face challenges in achieving high throughput due to limitations in parallel processing and uniform focal spot generation.
Existing scanning-based TPP approaches struggle to meet the demands for large-scale micro/nanofabrication.

Purpose of the Study:

To develop a novel TPP printing platform that significantly enhances fabrication speed and throughput.
To overcome the limitations of generating uniform focal spots for parallel high-speed scanning in TPP.
To demonstrate the capability of the new platform for rapid fabrication of functional 3D microstructures.

Main Methods:

Integration of galvanometric mirrors with a liquid crystal on silicon spatial light modulator (LCoS-SLM) in a TPP system.
Optimization of light field settings on the LCoS-SLM to generate over 400 simultaneous polymerization foci.
Implementation of fast scanning strategies for high-speed voxel deposition.

Main Results:

Achieved a maximum printing speed of 1.49 × 10⁸ voxels s^-1, surpassing existing scanning-based TPP methods.
Maintained high printing resolution and flexibility with the parallel processing approach.
Successfully fabricated functional 3D microstructure arrays for applications in micro-optics and micro-object manipulation.

Conclusions:

The developed TPP platform offers a significant advancement in micro/nano additive manufacturing throughput.
The combination of galvanometric mirrors and LCoS-SLM enables efficient parallel processing for high-speed 3D printing.
This technology holds promise for expanding the applications of TPP in large-scale micro/nanofabrication.