Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Electrical Synapses01:28

Electrical Synapses

8.3K
Electrical synapses found in all nervous systems play important and unique roles. In these synapses, the presynaptic and postsynaptic membranes are very close together (3.5 nm) and are actually physically connected by channel proteins forming gap junctions.
Gap junctions allow the current to pass directly from one cell to the next. In contrast, in the chemical synapse, the neurotransmitters carry the information through the synaptic cleft from one neuron to the next. They consist of two...
8.3K
Bacterial Signaling01:30

Bacterial Signaling

32.1K
Bacterial signaling can occur within bacteria (intracellular) or between bacteria (intercellular). At times, a group of bacteria behaves like a community. To achieve this, they engage in quorum sensing, the perception of higher cell density that causes changes in gene expression. Quorum sensing involves both extracellular and intracellular signaling. The signaling cascade starts with a molecule called an autoinducer (AI). Individual bacteria produce AIs that move out of the bacterial cell...
32.1K
Electrophysiology of Normal Cardiac Rhythm01:19

Electrophysiology of Normal Cardiac Rhythm

4.3K
The normal cardiac rhythm is a synchronized electrical activity that facilitates the regular and coordinated contraction of the heart muscle. This process is essential for efficient blood circulation throughout the body. The fundamental elements involved in establishing and maintaining this rhythm include the unique electrical properties of cardiac muscle cells, the sinoatrial (SA) node's pacemaker function, the specialized conducting system, and the ionic mechanisms underlying each phase...
4.3K
Electrochemical Gradient and Channel Proteins: An Overview01:21

Electrochemical Gradient and Channel Proteins: An Overview

2.2K
An electrochemical gradient is a fundamental concept in biology and chemistry. It regulates the movement of ions across cell membranes. This movement is influenced by two factors:
The electrical gradient: The electrical gradient across cell membranes refers to the difference in electric charge between the inside and outside of a cell.  This difference drives the movement of ions towards or away from the cells. For instance, if the inside of the cell is more negatively charged relative to...
2.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A Minimalist Model Lipid System Mimicking the Biophysical Properties of <i>Escherichia coli</i>'s Inner Membrane.

Langmuir : the ACS journal of surfaces and colloids·2025
Same author

Environmental conditions define the energetics of bacterial dormancy and its antibiotic susceptibility.

Biophysical journal·2023
Same author

Coordination of gene expression with cell size enables <i>Escherichia coli</i> to efficiently maintain motility across conditions.

Proceedings of the National Academy of Sciences of the United States of America·2022
Same author

Steady-state running rate sets the speed and accuracy of accumulation of swimming bacteria.

Biophysical journal·2022
Same author

Growth-dependent heterogeneity in the DNA damage response in Escherichia coli.

Molecular systems biology·2022
Same author

Understanding Beta-Lactam-Induced Lysis at the Single-Cell Level.

Frontiers in microbiology·2021

Related Experiment Video

Updated: Jul 2, 2025

Translating Extracellular Electron Transfer Activities with Organic Electrochemical Transistors
10:44

Translating Extracellular Electron Transfer Activities with Organic Electrochemical Transistors

Published on: January 31, 2025

610

Bacterial Electrophysiology.

Wei-Chang Lo1, Ekaterina Krasnopeeva2, Teuta Pilizota3

  • 1Institute of Physics, Academia Sinica, Taipei, Taiwan.

Annual Review of Biophysics
|February 21, 2024
PubMed
Summary
This summary is machine-generated.

This review revisits bacterial electrophysiology, focusing on membrane potential. It explores measurement challenges and methods for understanding bacterial ion transport and energy generation.

Keywords:
bacteriabiophysical modelselectrophysiologyion fluxesmembrane potentialpump-leak equations

More Related Videos

Characterizing Mediated Extracellular Electron Transfer in Lactic Acid Bacteria with a Three-Electrode, Two-Chamber Bioelectrochemical System
10:23

Characterizing Mediated Extracellular Electron Transfer in Lactic Acid Bacteria with a Three-Electrode, Two-Chamber Bioelectrochemical System

Published on: August 23, 2024

787
Electroporation of Mycobacteria
11:57

Electroporation of Mycobacteria

Published on: May 23, 2008

25.4K

Related Experiment Videos

Last Updated: Jul 2, 2025

Translating Extracellular Electron Transfer Activities with Organic Electrochemical Transistors
10:44

Translating Extracellular Electron Transfer Activities with Organic Electrochemical Transistors

Published on: January 31, 2025

610
Characterizing Mediated Extracellular Electron Transfer in Lactic Acid Bacteria with a Three-Electrode, Two-Chamber Bioelectrochemical System
10:23

Characterizing Mediated Extracellular Electron Transfer in Lactic Acid Bacteria with a Three-Electrode, Two-Chamber Bioelectrochemical System

Published on: August 23, 2024

787
Electroporation of Mycobacteria
11:57

Electroporation of Mycobacteria

Published on: May 23, 2008

25.4K

Area of Science:

  • Microbiology
  • Biophysics

Background:

  • Bacterial ion fluxes are crucial for energy generation, transport, and motility.
  • Bacterial electrophysiology is fundamental to the bacterial life cycle but remains poorly understood.
  • Challenges include measuring variables in small cells and the complex interplay of factors in unicellular organisms.

Purpose of the Study:

  • To provide a foundational understanding of bacterial electrophysiology.
  • To review biophysical principles of bacterial membrane potential.
  • To assess the applicability of established electrophysiological methods to bacteria.

Main Methods:

  • Review of biophysical principles of bacterial membrane potential.
  • Adaptation of methods from neuronal and mitochondrial electrophysiology.
  • Discussion of techniques for measuring and influencing bacterial electrophysiology.

Main Results:

  • Bacterial membrane potential is a key variable influenced by ion fluxes.
  • Existing electrophysiological models require adaptation for bacterial systems.
  • A range of methods exist to measure and manipulate bacterial electrophysiology.

Conclusions:

  • A comprehensive understanding of bacterial electrophysiology is essential.
  • Further research is needed to refine and apply electrophysiological techniques to bacteria.
  • This review provides a framework for future studies in bacterial electrophysiology.