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Updated: Jul 2, 2025

Author Spotlight: THP-1 Macrophage Response to LPS/ATP — Unveiling the Pyroptosis, Apoptosis, and Necroptosis Spectrum
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TMAO promotes vascular endothelial cell pyroptosis via the LPEAT-mitophagy pathway

Yanmei Chen1, Chuchu Yuan2, Wenhua Qin2

  • 1Institute of Cardiovascular Disease, Key Laboratory for Arteriosclerology of Hunan Province, Hunan International Scientific and Technological Cooperation Base of Arteriosclerotic Disease, Hengyang Medical School, University of South China, Hengyang, Hunan, 421001, China; Department of Pathology, Southwest Hospital, Army Medical University, Chongqing, 400038, China.

Biochemical and Biophysical Research Communications
|February 21, 2024
PubMed

Keywords:
AtherosclerosisEndothelial cell damageLPEATMitophagyPyroptosisTMAO

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