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A Case of Ertapenem-Induced Delirium
Maria Aquilina1, Nicole Galdes1, Neville Spiteri2
1Surgery, Mater Dei Hospital, Msida, MLT.
Abstract:
Ertapenem is a carbapenem antibiotic that is typically prescribed in cases of moderate-to-severe infections, especially ones involving abscess formation. We describe the case of an 82-year-old gentleman who presented with osteomyelitis and abscess formation who developed delirium after 15 days of ertapenem treatment. The patient experienced delusions, insomnia, agitation, and disorientation. The patient's mental status improved and returned to his baseline within 48 hours of halting ertapenem treatment. A high index of suspicion is required to identify and treat ertapenem-induced delirium. Withdrawal of ertapenem treatment in such cases usually results in a complete resolution of symptoms.
Insights
Ertapenem, a common antibiotic for severe infections, can cause delirium in elderly patients. Stopping the medication typically resolves these neurological side effects, highlighting the need for careful monitoring.
Area of Science:
- Pharmacology
- Neurology
- Infectious Diseases
Background:
- Ertapenem is a carbapenem antibiotic used for moderate-to-severe infections, particularly those with abscesses.
- Delirium is a serious neurological condition that can manifest with confusion, agitation, and disorientation.
