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Related Concept Videos

Cryptococcal Meningitis01:27

Cryptococcal Meningitis

Cryptococcal meningitis is a life-threatening opportunistic infection predominantly associated with HIV/AIDS, accounting for over 100,000 deaths annually worldwide. However, it also affects individuals with other forms of immunosuppression, including those undergoing immunosuppressive therapy, organ transplant recipients, patients with innate immunodeficiencies, and individuals with hematological disorders. The infection is caused mainly by Cryptococcus neoformans and Cryptococcus gattii,...

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A Case of Bilateral Cryptococcal Olecranon Bursitis.

Saverio Francesco Bianco1, Andrea Noah Paris2, Nicole Galdes2

  • 1Orthopaedics and Trauma, Mater Dei Hospital, Msida, MLT.

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|August 13, 2024
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Summary

Septic olecranon bursitis (SOB) caused by Cryptococcus neoformans is rare, even in immunocompetent individuals. This case highlights the importance of considering unusual pathogens for timely diagnosis and effective treatment.

Keywords:
bursectomybursitiscryptococcus neoformansfungalolecranonseptic

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Area of Science:

  • Infectious Diseases
  • Rheumatology
  • Surgical Pathology

Background:

  • Non-septic olecranon bursitis (NSOB) typically presents with aseptic symptoms and is self-limiting.
  • Septic olecranon bursitis (SOB) is commonly caused by bacterial pathogens and may require medical or surgical intervention.

Observation:

  • A previously healthy, immunocompetent 24-year-old female presented with bilateral septic olecranon bursitis.
  • Fluid cultures revealed Cryptococcus neoformans, indicating a disseminated cryptococcal infection.

Findings:

  • The patient underwent bilateral olecranon bursectomy, washouts, and debridement.
  • Treatment included intravenous amphotericin B, followed by oral flucytosine and fluconazole, resulting in good clinical outcomes at one-year follow-up.

Implications:

  • Disseminated infections from unusual pathogens like Cryptococcus neoformans in SOB are rare, particularly in immunocompetent hosts.
  • The subtle and insidious nature of these infections can delay diagnosis and treatment, increasing morbidity.
  • Early consideration of atypical organisms and consultation with infectious disease specialists are crucial for managing such rare cases.