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Updated: Jul 2, 2025

Cell Population Analyses During Skin Carcinogenesis
Published on: August 21, 2013
Basal cell carcinoma appearing to emanate from the punctum
Tom Kornhauser1, James S Nix2, John D Pemberton1
1Jones Eye Institute, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Purpose:
To present the clinical and histological characteristics of a basal cell carcinoma, which appears to emanate from the lacrimal punctum.
Observations:
An 81-year-old caucasian female presented with an irritating lesion arising from the left upper punctum for approximately four months. Examination demonstrated a pedunculated pinkish lesion emerging from the left upper punctum. The patient elected to pursue the removal of the lesion. An excisional biopsy was performed by placing a curette within the upper eyelid punctum, and the lesion was scooped out. Pathology showed invasive nodular basal cell carcinoma. Following the diagnosis, a wedge resection of the left upper punctal region was performed, which showed no residual carcinoma.
Conclusion And Importance:
This case describes a unique instance of a basal cell carcinoma clinically appearing to arise solely from the upper eyelid punctum. A level of suspicion should be maintained when excising benign-appearing eyelid lesions, and a histopathological analysis is warranted.
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