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Updated: Jul 27, 2026

A Protocol for Rapid Post-mortem Cell Culture of Diffuse Intrinsic Pontine Glioma DIPG
Published on: March 7, 2017
Protocol for investigating data quality and reporting outcomes of pediatric gliomas in population-based cancer
Raoull Hoogendijk1, Jasper van der Lugt1, Mariëtte E G Kranendonk1
1Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands.
Abstract:
Cancer registry data on pediatric gliomas come with inherent limitations as inclusion criteria and registration practices of these tumors differ between registries due to specific guidelines that are lacking. These limitations can lead to biased estimates in incidence and survival outcomes. Here, we present a protocol to investigate data quality and comparability for retrospective population-based pediatric glioma studies. We describe steps for obtaining institutional permissions, dealing with data quality issues, regrouping tumors, and reporting tumors in a clinically relevant manner. For complete details on the use and execution of this protocol, please refer to Hoogendijk et al.1.
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