Tribological behavior and in vitro biocompatibility of powder metallurgical Ti-15Mo/HA composite for bone repair
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Updated: Jul 2, 2025
Biological Compatibility Profile on Biomaterials for Bone Regeneration
Published on: November 16, 2018
Fangxia Xie1, Qichao Sun2, Yanming Mu1
1School of Mechanical Engineering, Jiangnan University, Wuxi, 214122, China; Key Laboratory of Advanced Food Manufacturing Equipment and Technology, Wuxi, 214122, China.
Abstract:
Ti-15Mo/HA composite was prepared by powder metallurgy, and the influence of Hydroxyapatite (HA) on the microstructure, tribological behavior and in vitro biocompatibility was studied by comparison with TC4. The results show that the Ti-15Mo/HA composite consists of increased α-Ti, decreased β-Ti and a variety of ceramic phases (CaTiO3, Ca3(PO4)2, CaO, etc.) with the increase of HA content. The friction coefficient and wear rate of Ti-15Mo/HA composite is apparently lower than those of TC4 due to solid solution strengthening of Mo in Ti and dispersion strengthening of ceramic phases. Ti-15Mo/5HA displays more excellent wear resistance than the other composite. TC4 alloy is dominated by adhesive wear, however, Ti-15Mo alloy is a combination of adhesive wear and abrasive wear. Ti-15Mo/HA composite is mainly subjected to abrasive wear, together with adhesive wear. The viability and the number of mouse osteoblasts in Ti-15Mo/5HA extract are higher than that of Ti-15Mo. The morphology of the osteoblasts is clear and full, and the growth and proliferation are satisfactory with the increased cell pseudopodia with the culture time. The Ti-15Mo/HA composite displays good wear resistance and biocompatibility, and accordingly has a potential application in bone repair materials.
